C
Cécile Huin-Schohn
Researcher at University of Luxembourg
Publications - 8
Citations - 354
Cécile Huin-Schohn is an academic researcher from University of Luxembourg. The author has contributed to research in topics: Spaceflight & Internal medicine. The author has an hindex of 4, co-authored 6 publications receiving 318 citations.
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Journal ArticleDOI
Could spaceflight-associated immune system weakening preclude the expansion of human presence beyond Earth’s orbit?
Nathan Guéguinou,Cécile Huin-Schohn,Matthieu Bascove,Jean-Luc Bueb,Eric Tschirhart,Christine Legrand-Frossi,Jean-Pol Frippiat +6 more
TL;DR: Major constraints associated with a trip to Mars are summarized, immunological hazards associated with this type of mission are presented, and it is shown that current understanding of the immunosuppressive effects of spaceflight is limited.
Journal ArticleDOI
Spaceflight-associated changes in immunoglobulin VH gene expression in the amphibian Pleurodeles waltl
TL;DR: Different heavy‐chain mRNAs are expressed by spaceflight animals, demonstrating that this environment affects the humoral response, and a change in B‐cell selection under space flight conditions is observed.
Journal ArticleDOI
Gravity changes during animal development affect IgM heavy-chain transcription and probably lymphopoiesis
Cécile Huin-Schohn,Nathan Guéguinou,Véronique Schenten,Matthieu Bascove,Guillemette Gauquelin Koch,Sarah Baatout,Eric Tschirhart,Jean-Pol Frippiat +7 more
TL;DR: It is found that IgM heavy‐chain transcription is doubled at landing and that spaceflight does not affect P. waltl development and does not induce inflammation, suggesting a modification of lymphopoiesis when gravity changes occur during ontogeny.
Journal ArticleDOI
Molecular cloning and expression analysis of Pleurodeles waltl complement component C3 under normal physiological conditions and environmental stresses.
Nathan Guéguinou,Cécile Huin-Schohn,Nassima Ouzren-Zarhloul,Stéphanie Ghislin,Jean-Pol Frippiat +4 more
TL;DR: Quantitative real-time PCR (qRT-PCR) demonstrated that under normal physiological conditions, P. waltl C3 mRNA is expressed early during development because it is likely required for neurulation, and its expression increased as the immune system developed.
presence beyond Earth's orbit? Could spaceflight-associated immune system weakening preclude the expansion of human
Duane L. Pierson,Christine Smid,L Daniel,Indreshpal Kaur,Elizabeth R. Simons,Asha S. Kapadia,C. Mark Ott,Virginia L. Ferguson,Michael J. Pecaut,Daila S. Gridley,James M. Slater,Xian Luo-Owen,Asma Rizvi,Stephen K. Chapes,S Louis,Christine Legrand-Frossi,Jean-Pol Frippiat,Nathan Guéguinou,Cécile Huin-Schohn,Matthieu Bascove,Jean-Luc Bueb,Eric Tschirhart +21 more