C
Cecilia Pessoa Rodrigues
Researcher at Max Planck Society
Publications - 6
Citations - 431
Cecilia Pessoa Rodrigues is an academic researcher from Max Planck Society. The author has contributed to research in topics: Histone H4 & Chemistry. The author has an hindex of 3, co-authored 6 publications receiving 279 citations. Previous affiliations of Cecilia Pessoa Rodrigues include University of Freiburg Faculty of Biology & University of Freiburg.
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Journal ArticleDOI
DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome
Tugce Aktas,Ibrahim Avsar Ilik,Daniel Maticzka,Vivek Bhardwaj,Vivek Bhardwaj,Cecilia Pessoa Rodrigues,Cecilia Pessoa Rodrigues,Gerhard Mittler,Thomas Manke,Rolf Backofen,Asifa Akhtar +10 more
TL;DR: It is proposed that DHX9 acts as a nuclear RNA resolvase that neutralizes the immediate threat posed by transposon insertions and allows these elements to evolve as tools for the post-transcriptional regulation of gene expression.
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Epigenetic Regulators as the Gatekeepers of Hematopoiesis
TL;DR: What is currently known about chromatin status and the development of cells in the hematopoietic system under normal and abnormal conditions are brought together.
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Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate
Cecilia Pessoa Rodrigues,Cecilia Pessoa Rodrigues,Josip S. Herman,Josip S. Herman,Benjamin Herquel,Claudia Isabelle Keller Valsecchi,Thomas Stehle,Dominic Grün,Dominic Grün,Asifa Akhtar,Asifa Akhtar +10 more
TL;DR: The mechanism by which histone H4 lysine 16 acetyltransferase MOF regulates erythropoiesis is explored, revealing that MOF influences erythroid trajectory by dynamic recruitment to chromatin and its haploinsufficiency causes accumulation of a transient HSC population.
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Histone H4 lysine 16 acetylation controls central carbon metabolism and diet-induced obesity in mice.
Cecilia Pessoa Rodrigues,Cecilia Pessoa Rodrigues,Aindrila Chatterjee,Meike Wiese,Thomas Stehle,Witold G. Szymanski,Maria Shvedunova,Asifa Akhtar,Asifa Akhtar +8 more
TL;DR: In this article, the H4 lysine 16 acetyltransferase (H4K16ac) was identified as a critical regulator of central carbon metabolism in type 2 diabetes.
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Differential H4K16ac levels ensure a balance between quiescence and activation in hematopoietic stem cells
TL;DR: In this paper, the levels of the histone acetyltransferase (males absent on the first) and its target modification histone H4 lysine 16 acetylation are heterogeneous among HSCs and influence their proliferation capacities.