C
Cédric Beaucamps
Researcher at French Institute of Health and Medical Research
Publications - 1
Citations - 521
Cédric Beaucamps is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Glucose transporter & Alpha cell. The author has an hindex of 1, co-authored 1 publications receiving 464 citations.
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Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
Caroline Bonner,Julie Kerr-Conte,Valery Gmyr,Gurvan Queniat,Ericka Moerman,Julien Thevenet,Cédric Beaucamps,Nathalie Delalleau,Iuliana Popescu,Willy Malaisse,Abdullah Sener,Benoit Deprez,Amar Abderrahmani,Bart Staels,François Pattou +14 more
TL;DR: It is demonstrated that SGLT2 is expressed in glucagon-secreting alpha cells of the pancreatic islets, and dapagliflozin treatment further promotes glucagon secretion and hepatic gluconeogenesis in healthy mice, thereby limiting the decrease of plasma glucose induced by fasting.