C
Céline Méhats
Researcher at Paris Descartes University
Publications - 63
Citations - 2595
Céline Méhats is an academic researcher from Paris Descartes University. The author has contributed to research in topics: Pregnancy & Phosphodiesterase. The author has an hindex of 23, co-authored 56 publications receiving 2304 citations. Previous affiliations of Céline Méhats include French Institute of Health and Medical Research & Centre national de la recherche scientifique.
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Journal ArticleDOI
Cyclic AMP-specific PDE4 phosphodiesterases as critical components of cyclic AMP signaling.
Journal ArticleDOI
Role of cyclic nucleotide signaling in oocyte maturation
Marco Conti,Carsten B Andersen,Francois Richard,Céline Méhats,Sang Young Chun,Kathleen Horner,Catherine Jin,Alex Tsafriri +7 more
TL;DR: PDE3 plays an essential role in the signaling pathway that controls resumption of meiosis in amphibians and mammals, and understanding the regulation of this enzyme may shed some light on the signals that trigger oocyte maturation.
Journal ArticleDOI
Cyclic nucleotide phosphodiesterases and their role in endocrine cell signaling
TL;DR: This review explores the involvement of PDEs in the regulation of intracellular signaling and focuses on the known and potential roles that are of interest to endocrinologists.
Journal ArticleDOI
PDE4D plays a critical role in the control of airway smooth muscle contraction.
TL;DR: It is demonstrated that PDE4D plays a key role in balancing relaxant and contracting cues in airway smooth muscle, suggesting that natural mutations in the Pde4D gene have profound effects on airway tone.
Journal ArticleDOI
Preeclampsia-Like Symptoms Induced in Mice by Fetoplacental Expression of STOX1 Are Reversed by Aspirin Treatment
Ludivine Doridot,Bruno Passet,Céline Méhats,Virginie Rigourd,Sandrine Barbaux,Aurélien Ducat,Françoise Mondon,Marthe Vilotte,Johann Castille,Michelle Breuiller-Fouché,Nathalie Daniel,Fabienne Le Provost,Anne-Laure Bauchet,Véronique Baudrie,Alexandre Hertig,Christophe Buffat,Umberto Simeoni,Guy Germain,Jean-Luc Vilotte,Daniel Vaiman +19 more
TL;DR: Transgenic mouse strains overexpressing human STOX1-overexpressing mice constitute a unique model for studying PE, allowing testing therapeutic approaches, and assessing the long-term effects of the preeclamptic syndrome.