C
Changjiang Liu
Researcher at National Health and Family Planning Commission
Publications - 2
Citations - 147
Changjiang Liu is an academic researcher from National Health and Family Planning Commission. The author has contributed to research in topics: Phthalate & Hormone receptor. The author has an hindex of 2, co-authored 2 publications receiving 110 citations.
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Di-(2-ethylhexyl) phthalate inhibits testosterone level through disturbed hypothalamic-pituitary-testis axis and ERK-mediated 5α-Reductase 2.
TL;DR: Results indicated that the hypothalamic-pituitary-testis (HPT) axis was disturbed and serum testosterone, LH and FSH levels were decreased following DEHP exposure, and taken together, DEHP-disturbed HPT axis and induced 5α-Reductase 2 contribute to the reduction of serum testosterone level.
Journal ArticleDOI
Di2-ethylhexyl phthalate disrupts thyroid hormone homeostasis through activating the Ras/Akt/TRHr pathway and inducing hepatic enzymes
TL;DR: Taken together, DEHP can perturb TH homeostasis and reduce TH levels and the activated Ras/Akt/TRHr pathway and induced hepatic enzymes play vital roles in thyroid-disrupting effects of DEHP.