K
Karen J. Brasel
Researcher at Medical College of Wisconsin
Publications - 268
Citations - 13904
Karen J. Brasel is an academic researcher from Medical College of Wisconsin. The author has contributed to research in topics: Poison control & Injury Severity Score. The author has an hindex of 58, co-authored 244 publications receiving 12050 citations. Previous affiliations of Karen J. Brasel include University of Wisconsin–Milwaukee & Oregon Health & Science University.
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Journal ArticleDOI
Transfusion of plasma, platelets, and red blood cells in a 1: 1:1 vs a 1:1:2 ratio and mortality in patients with severe trauma: The PROPPR randomized clinical trial
John B. Holcomb,Barbara C. Tilley,Sarah Baraniuk,Erin E. Fox,Charles E. Wade,Jeanette M. Podbielski,Deborah J. del Junco,Karen J. Brasel,Karen J. Brasel,Eileen M. Bulger,Rachael A. Callcut,Mitchell J. Cohen,Bryan A. Cotton,Timothy C. Fabian,Kenji Inaba,Jeffrey D. Kerby,Peter Muskat,Peter Muskat,Terence O'Keeffe,Sandro Rizoli,Bryce R.H. Robinson,Thomas M. Scalea,Martin A. Schreiber,Deborah M. Stein,Jordan A. Weinberg,Jeannie Callum,John R. Hess,Nena Matijevic,Christopher N. Miller,Jean-Francois Pittet,David B. Hoyt,Gail D. Pearson,Brian G. Leroux,Gerald van Belle +33 more
TL;DR: In this article, the effectiveness and safety of transfusing patients with severe trauma and major bleeding using plasma, platelets, and red blood cells in a 1:1:1 ratio compared with a 1 :1:2 ratio was evaluated.
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The prospective, observational, multicenter, major trauma transfusion (PROMMTT) study: Comparative effectiveness of a time-varying treatment with competing risks
John B. Holcomb,Deborah J. del Junco,Erin E. Fox,Charles E. Wade,Mitchell J. Cohen,Martin A. Schreiber,Louis H. Alarcon,Yu Bai,Karen J. Brasel,Eileen M. Bulger,Bryan A. Cotton,Nena Matijevic,Peter Muskat,John G. Myers,Herb A. Phelan,Christopher E. White,Jiajie Zhang,Mohammad H. Rahbar +17 more
TL;DR: Higher plasma and platelet ratios early in resuscitation were associated with decreased mortality in patients who received transfusions of at least 3 units of blood products during the first 24 hours after admission, and among survivors at 24 hours, the subsequent risk of death by day 30 was not associated with plasma or Platelet ratios.
Journal ArticleDOI
Advanced trauma life support, 8th edition, the evidence for change.
John B. Kortbeek,Saud A. Al Turki,Jameel Ali,Jill A. Antoine,B. Bouillon,Karen J. Brasel,Fred Brenneman,Peter Rinze Gérard Brink,Karim Brohi,David Burris,Reginald A. Burton,Will Chapleau,Wiliam Cioffi,Francisco de Salles Collet e Silva,Art Cooper,Jaime A. Cortes,Vagn Eskesen,John J. Fildes,Subash Gautam,Russell L. Gruen,Ron Gross,K. S. Hansen,Walter Henny,Michael J. Hollands,Richard C. Hunt,Jose M. Jover Navalon,Christoph Kaufmann,Peggy Knudson,Amy Koestner,Roman Kosir,Claus Falck Larsen,West Livaudais,Fred A. Luchette,Patrizio Mao,John H. McVicker,Jay Wayne Meredith,Charles Mock,Newton Djin Mori,Charles E. Morrow,Steven N. Parks,Steven N. Parks,Pedro Moniz Pereira,Renato Sergio Pogetti,Jesper Ravn,Peter Rhee,Jeffrey P. Salomone,Inger B. Schipper,Patrick Schoettker,Martin A. Schreiber,R. Stephen Smith,Lars Bo Svendsen,Wa'el Taha,Mary van Wijngaarden-Stephens,Endre Varga,E. J. Voiglio,Daryl Williams,Robert J. Winchell,Robert Winter +57 more
TL;DR: The 8th edition of ATLS has been revised following broad input by the International ATLS subcommittee and grades levels of evidence were used to evaluate and approve changes to the course content.
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Whole body imaging in blunt multisystem trauma patients without obvious signs of injury: Results of a prospective study
Ali Salim,Burapat Sangthong,Matthew J. Martin,Carlos V.R. Brown,David Plurad,Demetrios Demetriades,James G. Tyburski,Tyler G. Hughes,J. Stephen Marshall,Karen J. Brasel,Richard L. Jamison,Baiba J. Grube +11 more
TL;DR: The use of pan scan based on mechanism in awake, evaluable patients is warranted, and Clinically significant abnormalities are not uncommon, resulting in a change in treatment in nearly 19% of patients.
Journal ArticleDOI
Models for structuring a clinical initiative to enhance palliative care in the intensive care unit: A report from the IPAL-ICU Project (Improving Palliative Care in the ICU)
Judith E. Nelson,Rick Bassett,Renee D. Boss,Karen J. Brasel,Margaret L. Campbell,Therese B. Cortez,J. Randall Curtis,Dana Lustbader,Colleen Mulkerin,Kathleen Puntillo,Daniel E. Ray,David E. Weissman +11 more
TL;DR: There are two main models for intensive care unit-palliative care integration: 1) the “consultative model,” which focuses on increasing the involvement and effectiveness of palliative Care consultants in the care ofintensive care unit patients and their families, particularly those patients identified as at highest risk for poor outcomes.