C
Charles F. Gillespie
Researcher at Emory University
Publications - 76
Citations - 6714
Charles F. Gillespie is an academic researcher from Emory University. The author has contributed to research in topics: Population & Child abuse. The author has an hindex of 28, co-authored 71 publications receiving 5584 citations. Previous affiliations of Charles F. Gillespie include Georgia State University.
Papers
More filters
Journal ArticleDOI
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.
Elisabeth B. Binder,Rebekah Bradley,Rebekah Bradley,Wei Liu,Michael P. Epstein,Todd C. Deveau,Kristina B. Mercer,Yi-Lang Tang,Charles F. Gillespie,Christine Heim,Charles B. Nemeroff,Ann C. Schwartz,Joseph F. Cubells,Kerry J. Ressler,Kerry J. Ressler +14 more
TL;DR: There were no main effects of the SNPs on PTSD symptoms and no significant genetic interactions with level of non-child abuse trauma as predictor of adult PTSD symptoms, suggesting a potential gene-childhood environment interaction for adult PTSD.
Journal ArticleDOI
Influence of child abuse on adult depression: moderation by the corticotropin-releasing hormone receptor gene.
Rebekah Bradley,Elisabeth B. Binder,Michael P. Epstein,Yi-Lang Tang,Hemu P. Nair,Wei Liu,Charles F. Gillespie,Tiina Berg,Mark Evces,D. Jeffrey Newport,Zachary N. Stowe,Christine Heim,Charles B. Nemeroff,Ann C. Schwartz,Joseph F. Cubells,Kerry J. Ressler +15 more
TL;DR: Data support the corticotropin-releasing hormone hypothesis of depression and suggest that a gene x environment interaction is important for the expression of depressive symptoms in adults with CRHR1 risk or protective alleles who have a history of child abuse.
Journal ArticleDOI
Trauma exposure and stress-related disorders in inner city primary care patients
Charles F. Gillespie,Bekh Bradley,Kristie Mercer,Alicia K. Smith,Karen N. Conneely,Mark Gapen,Tamara Weiss,Ann C. Schwartz,Joseph F. Cubells,Kerry J. Ressler,Kerry J. Ressler,Kerry J. Ressler +11 more
TL;DR: These data document high levels of childhood and adult trauma exposure, principally interpersonal violence, in a large sample of an inner-city primary care population and predictors of posttraumatic stress and depressive symptomatology.
Journal ArticleDOI
Inflammation in Fear- and Anxiety-Based Disorders: PTSD, GAD, and Beyond.
Vasiliki Michopoulos,Vasiliki Michopoulos,Abigail Powers,Charles F. Gillespie,Kerry J. Ressler,Tanja Jovanovic +5 more
TL;DR: The available data suggest that targeting inflammation may serve as a potential therapeutic target for treating fear- and anxiety-based disorders in the future, but the field must continue to characterize the specific role pro-inflammatory signaling in the maintenance of these unique psychiatric conditions.
Journal ArticleDOI
Hypercortisolemia and depression.
TL;DR: The authors review the history of techniques used to assess the functions of the HPA axis, evidence for hypercortisolemia as a state rather than trait component of depression, and treatment implications.