C
Charles Frenette
Researcher at McGill University Health Centre
Publications - 49
Citations - 2585
Charles Frenette is an academic researcher from McGill University Health Centre. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 12, co-authored 35 publications receiving 2394 citations.
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Journal ArticleDOI
A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality.
Vivian G. Loo,Louise Poirier,Mark A. Miller,Matthew Oughton,Michael Libman,Sophie Michaud,Anne-Marie Bourgault,Tuyen Nguyen,Charles Frenette,Mirabelle Kelly,Anne Vibien,Paul Brassard,Susan Fenn,Ken Dewar,Thomas J. Hudson,Ruth Horn,Pierre René,Yury Monczak,Andre Dascal +18 more
TL;DR: A strain of C. difficile that was resistant to fluoroquinolones and had binary toxin and a partial deletion of the tcdC gene was responsible for this outbreak ofC.difficile-associated diarrhea.
Journal ArticleDOI
Continuous Proton Pump Inhibitor Therapy and the Associated Risk of Recurrent Clostridium difficile Infection.
Emily G. McDonald,Emily G. McDonald,Jonathon Milligan,Charles Frenette,Todd C. Lee,Todd C. Lee +5 more
TL;DR: Patients with continuous PPI use remained at elevated risk of CDI recurrence after adjustment for other independent predictors of recurrence, and it is suggested that the cessation of unnecessary P PI use should be considered at the time ofCDI diagnosis.
Journal ArticleDOI
Antibiotic Self-stewardship: Trainee-Led Structured Antibiotic Time-outs to Improve Antimicrobial Use
TL;DR: An educational curriculum and electronic checklist were developed to provide structure and mandatory time-out audits were integrated into routine clinical practice by senior residents, who performed a process that was called antimicrobial self-stewardship.
Journal ArticleDOI
Healthcare-associated influenza in Canadian hospitals from 2006 to 2012.
Geoffrey Taylor,Robyn Mitchell,Allison McGeer,Charles Frenette,Kathryn N. Suh,Alice Wong,Kevin Katz,Krista Wilkinson,Barbara Amihod,Denise Gravel +9 more
TL;DR: Healthy-associated influenza is a major component of the burden of disease from influenza in hospitals, but the proportion of cases that are healthcare associated varies markedly from year to year, as does theportion of healthcare-associated infections that are acquired in an ACF versus an LTCF.
Journal ArticleDOI
Central line-associated bloodstream infection in neonatal intensive care units.
Ana C. Blanchard,Elise Fortin,Isabelle Rocher,Dorothy Moore,Charles Frenette,Claude Tremblay,Caroline Quach +6 more
TL;DR: The increase in CLABSI rates in Quebec NICUs seems to be associated with an increased proportion of cases with underlying intra-abdominal and pulmonary pathologies, which needs further investigation.