K
Ken Dewar
Researcher at McGill University
Publications - 107
Citations - 31759
Ken Dewar is an academic researcher from McGill University. The author has contributed to research in topics: Genome & Gene. The author has an hindex of 47, co-authored 105 publications receiving 29820 citations. Previous affiliations of Ken Dewar include Montreal Neurological Institute and Hospital & Broad Institute.
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Journal ArticleDOI
Initial sequencing and analysis of the human genome.
Eric S. Lander,Lauren Linton,Bruce W. Birren,Chad Nusbaum,Michael C. Zody,Jennifer Baldwin,Keri Devon,Ken Dewar,Michael Doyle,William Fitzhugh,Roel Funke,Diane Gage,Katrina Harris,Andrew Heaford,John Howland,Lisa Kann,Jessica A. Lehoczky,Rosie Levine,Paul A. McEwan,Kevin McKernan,James Meldrim,Jill P. Mesirov,Cher Miranda,William Morris,Jerome Naylor,Christina Raymond,Mark Rosetti,Ralph Santos,Andrew Sheridan,Carrie Sougnez,Nicole Stange-Thomann,Nikola Stojanovic,Aravind Subramanian,Dudley Wyman,Jane Rogers,John Sulston,R Ainscough,Stephan Beck,David Bentley,John Burton,C M Clee,Nigel P. Carter,Alan Coulson,Rebecca Deadman,Panos Deloukas,Andrew Dunham,Ian Dunham,Richard Durbin,Lisa French,Darren Grafham,Simon G. Gregory,Tim Hubbard,Sean Humphray,Adrienne Hunt,Matthew Jones,Christine Lloyd,Amanda McMurray,Lucy Matthews,Simon Mercer,Sarah Milne,James C. Mullikin,Andrew J. Mungall,Robert W. Plumb,Mark T. Ross,Ratna Shownkeen,Sarah Sims,Robert H. Waterston,Richard K. Wilson,LaDeana W. Hillier,John Douglas Mcpherson,Marco A. Marra,Elaine R. Mardis,Lucinda Fulton,Asif T. Chinwalla,Kymberlie H. Pepin,Warren Gish,Stephanie L. Chissoe,Michael C. Wendl,Kim D. Delehaunty,Tracie L. Miner,Andrew Delehaunty,Jason B. Kramer,Lisa Cook,Robert S. Fulton,Douglas L. Johnson,Patrick Minx,Sandra W. Clifton,Trevor Hawkins,Elbert Branscomb,Paul Predki,Paul G. Richardson,Sarah Wenning,Tom Slezak,Norman A. Doggett,Jan Fang Cheng,Anne S. Olsen,Susan Lucas,Christopher J. Elkin,Edward Uberbacher,Marvin Frazier,Richard A. Gibbs,Donna M. Muzny,Steven E. Scherer,John Bouck,Erica Sodergren,Kim C. Worley,Catherine M. Rives,James H. Gorrell,Michael L. Metzker,Susan L. Naylor,Raju Kucherlapati,David L. Nelson,George M. Weinstock,Yoshiyuki Sakaki,Asao Fujiyama,Masahira Hattori,Tetsushi Yada,Atsushi Toyoda,Takehiko Itoh,Chiharu Kawagoe,Hidemi Watanabe,Yasushi Totoki,Todd D. Taylor,Jean Weissenbach,Roland Heilig,William Saurin,François Artiguenave,Philippe Brottier,Thomas Brüls,Eric Pelletier,Catherine Robert,Patrick Wincker,André Rosenthal,Matthias Platzer,Gerald Nyakatura,Stefan Taudien,Andreas Rump,Douglas R. Smith,Lynn Doucette-Stamm,Marc Rubenfield,Keith Weinstock,Mei Lee Hong,Joann Dubois,Huanming Yang,Jun Yu,Jian Wang,Guyang Huang,Jun Gu,Leroy Hood,Lee Rowen,Anup Madan,Shizen Qin,Ronald W. Davis,Nancy A. Federspiel,A. Pia Abola,Michael Proctor,Bruce A. Roe,Feng Chen,Huaqin Pan,Juliane Ramser,Hans Lehrach,Richard Reinhardt,W. Richard McCombie,Melissa De La Bastide,Neilay Dedhia,H. Blöcker,K. Hornischer,Gabriele Nordsiek,Richa Agarwala,L. Aravind,Jeffrey A. Bailey,Alex Bateman,Serafim Batzoglou,Ewan Birney,Peer Bork,Daniel G. Brown,Christopher B. Burge,Lorenzo Cerutti,Hsiu Chuan Chen,Deanna M. Church,Michele Clamp,Richard R. Copley,Tobias Doerks,Sean R. Eddy,Evan E. Eichler,Terrence S. Furey,James E. Galagan,James G. R. Gilbert,Cyrus L. Harmon,Yoshihide Hayashizaki,David Haussler,Henning Hermjakob,Karsten Hokamp,Wonhee Jang,L. Steven Johnson,Thomas A. Jones,Simon Kasif,Arek Kaspryzk,Scot Kennedy,W. James Kent,Paul Kitts,Eugene V. Koonin,Ian F Korf,David Kulp,Doron Lancet,Todd M. Lowe,Aoife McLysaght,Tarjei S. Mikkelsen,John V. Moran,Nicola Mulder,Victor J. Pollara,Chris P. Ponting,Greg Schuler,Jörg Schultz,Guy Slater,Arian F.A. Smit,Elia Stupka,Joseph Szustakowki,Danielle Thierry-Mieg,Jean Thierry-Mieg,Lukas Wagner,John W. Wallis,Raymond Wheeler,Alan Williams,Yuri I. Wolf,Kenneth H. Wolfe,Shiaw Pyng Yang,Ru Fang Yeh,Francis S. Collins,Mark S. Guyer,Jane Peterson,Adam Felsenfeld,Kris A. Wetterstrand,Richard M. Myers,Jeremy Schmutz,Mark Dickson,Jane Grimwood,David R. Cox,Maynard V. Olson,Rajinder Kaul,Christopher K. Raymond,Nobuyoshi Shimizu,Kazuhiko Kawasaki,Shinsei Minoshima,Glen A. Evans,Maria Athanasiou,Roger A. Schultz,Aristides Patrinos,Michael J. Morgan +248 more
TL;DR: The results of an international collaboration to produce and make freely available a draft sequence of the human genome are reported and an initial analysis is presented, describing some of the insights that can be gleaned from the sequence.
Journal ArticleDOI
A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality.
Vivian G. Loo,Louise Poirier,Mark A. Miller,Matthew Oughton,Michael Libman,Sophie Michaud,Anne-Marie Bourgault,Tuyen Nguyen,Charles Frenette,Mirabelle Kelly,Anne Vibien,Paul Brassard,Susan Fenn,Ken Dewar,Thomas J. Hudson,Ruth Horn,Pierre René,Yury Monczak,Andre Dascal +18 more
TL;DR: A strain of C. difficile that was resistant to fluoroquinolones and had binary toxin and a partial deletion of the tcdC gene was responsible for this outbreak ofC.difficile-associated diarrhea.
Journal ArticleDOI
Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease.
John D. Rioux,Mark J. Daly,Mark S. Silverberg,Kerstin Lindblad,Hillary Steinhart,Zane Cohen,Terrye Delmonte,Kerry Kocher,Katie Miller,Sheila Guschwan,Edward J. Kulbokas,Sinéad B. O'Leary,Ellen Winchester,Ken Dewar,Todd Green,Valerie Stone,Christine S. Chow,Albert Cohen,Diane Langelier,Gilles Lapointe,Daniel Gaudet,Janet Faith,Nancy Branco,Shelley B. Bull,Robin S. McLeod,Anne M. Griffiths,Alain Bitton,Gordon R. Greenberg,Eric S. Lander,Katherine A. Siminovitch,Thomas J. Hudson,Thomas J. Hudson +31 more
TL;DR: This work seeks to design a systematic approach for LD mapping and applies it to the localization of a gene (IBD5) conferring susceptibility to Crohn disease, and binds the region to a common haplotype that shows strong association with the disease and contains the cytokine gene cluster.
Journal ArticleDOI
An atlas of over 90,000 conserved noncoding sequences provides insight into crucifer regulatory regions
Annabelle Haudry,Adrian E. Platts,Emilio Vello,Douglas R. Hoen,Mickael Leclercq,Robert J. Williamson,Ewa Forczek,Zoé Joly-Lopez,Joshua G. Steffen,Khaled M. Hazzouri,Ken Dewar,John R. Stinchcombe,Daniel J. Schoen,Xiaowu Wang,Jeremy Schmutz,Christopher D. Town,Patrick P. Edger,J. Chris Pires,Karen S. Schumaker,David E. Jarvis,Terezie Mandáková,Martin A. Lysak,Erik van den Bergh,M. Eric Schranz,Paul M. Harrison,Alan M. Moses,Thomas E. Bureau,Stephen I. Wright,Mathieu Blanchette +28 more
TL;DR: In this paper, the authors report sequencing of genomes from three Brassicaceae species (Leavenworthia alabamica, Sisymbrium irio and Aethionema arabicum) and their joint analysis with six previously sequenced crucifer genomes.
Journal ArticleDOI
Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana
Athanasios Theologis,Joseph R. Ecker,Joseph R. Ecker,Curtis J. Palm,Nancy A. Federspiel,Nancy A. Federspiel,Samir Kaul,Owen White,Jose M. Alonso,Hootan Altafi,Rina Araujo,Cheryl Bowman,Shelise Brooks,Eugen Buehler,April Chan,Qimin Chao,Huaming Chen,Rosa Cheuk,Christina W. Chin,Mike K. Chung,Lane Conn,Aaron B. Conway,Andrew R. Conway,Todd Creasy,Ken Dewar,Patrick Dunn,Pelin Etgu,Tamara Feldblyum,Ji Dong Feng,Betty Fong,Claire Fujii,John Gill,Andrew D. Goldsmith,Brian J. Haas,Nancy F. Hansen,Beth Hughes,Lucas Huizar,Jonathan L. Hunter,Jennifer Jenkins,Chanda Johnson-Hopson,Shehnaz Khan,Elizabeth Khaykin,Christopher Kim,Hean L. Koo,Irina Kremenetskaia,David B. Kurtz,Andrea Kwan,Bao Lam,Stephanie Langin-Hooper,Andrew L. Lee,Jeong M. Lee,Catherine A. Lenz,Joycelyn H. Li,Ya Ping Li,Xiaoying Lin,Shirley X. Liu,Zhaoying A. Liu,Jason S. Luros,Rama Maiti,Andre Marziali,Andre Marziali,Jennifer Militscher,Molly Miranda,Michelle Nguyen,William C. Nierman,Brian I. Osborne,Grace Pai,Jeremy Peterson,Paul K. Pham,Michael G. Rizzo,Timothy Rooney,Don Rowley,Hitomi Sakano,Steven L. Salzberg,Jody R. Schwartz,Paul Shinn,Audrey Southwick,Hui Sun,Luke J. Tallon,Gabriel Tambunga,Mitsue J. Toriumi,Christopher D. Town,Teresa Utterback,Susan Van Aken,Maria Vaysberg,Valentina S. Vysotskaia,Valentina S. Vysotskaia,Michelle Walker,Dongying Wu,Guixia Yu,Claire M. Fraser,J. Craig Venter,Ronald W. Davis +92 more
TL;DR: The genome of the flowering plant Arabidopsis thaliana has five chromosomes and the sequence of the largest, chromosome 1, in two contigs of around 14.2 and 14.6 megabases is reported.