T
Todd C. Lee
Researcher at McGill University Health Centre
Publications - 166
Citations - 4118
Todd C. Lee is an academic researcher from McGill University Health Centre. The author has contributed to research in topics: Medicine & Randomized controlled trial. The author has an hindex of 20, co-authored 138 publications receiving 2672 citations. Previous affiliations of Todd C. Lee include McGill University & University of Toronto.
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Journal ArticleDOI
A Randomized Trial of Hydroxychloroquine as Postexposure Prophylaxis for Covid-19.
David R. Boulware,Matthew F Pullen,Ananta S. Bangdiwala,Katelyn A Pastick,Sarah M Lofgren,Elizabeth C Okafor,Caleb P Skipper,Alanna A Nascene,Melanie R. Nicol,Mahsa Abassi,Nicole W. Engen,Matthew P. Cheng,Derek LaBar,Sylvain A. Lother,Lauren J. MacKenzie,Glen Drobot,Nicole Marten,Ryan Zarychanski,Lauren E. Kelly,Ilan S. Schwartz,Emily G. McDonald,Radha Rajasingham,Todd C. Lee,Kathy H. Hullsiek +23 more
TL;DR: After high-risk or moderate-risk exposure to Covid-19, hydroxychloroquine did not prevent illness compatible with Covid -19 or confirmed infection when used as postexposure prophylaxis within 4 days after exposure.
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Hydroxychloroquine in Nonhospitalized Adults With Early COVID-19 : A Randomized Trial.
Caleb P Skipper,Katelyn A Pastick,Nicole S Engen,Ananta S Bangdiwala,Mahsa Abassi,Sarah M Lofgren,Darlisha A. Williams,Elizabeth C Okafor,Matthew F Pullen,Melanie R. Nicol,Alanna A Nascene,Katherine Huppler Hullsiek,Matthew P. Cheng,Darlette Luke,Sylvain A. Lother,Lauren J. MacKenzie,Glen Drobot,Lauren E. Kelly,Ilan S. Schwartz,Ryan Zarychanski,Emily G. McDonald,Todd C. Lee,Radha Rajasingham,David R. Boulware +23 more
TL;DR: This randomized, double-blind, placebo-controlled trial evaluated effects of oral hydroxychloroquine on symptoms and disease severity in adult outpatients with early COVID-19.
Journal ArticleDOI
Comparison of Saliva and Nasopharyngeal Swab Nucleic Acid Amplification Testing for Detection of SARS-CoV-2: A Systematic Review and Meta-analysis.
Guillaume Butler-Laporte,Alexander Lawandi,Ian Schiller,Mandy Yao,Nandini Dendukuri,Emily G. McDonald,Emily G. McDonald,Todd C. Lee,Todd C. Lee +8 more
TL;DR: In this article, the authors conducted a systematic review to assess the diagnostic accuracy of saliva nucleic acid amplification testing (NAAT) for coronavirus disease 2019 (COVID-19) and concluded that salivary NAAT diagnostic accuracy is similar to that of nasopharyngeal swab NAAT, especially in the ambulatory setting.
Journal ArticleDOI
Continuous Proton Pump Inhibitor Therapy and the Associated Risk of Recurrent Clostridium difficile Infection.
Emily G. McDonald,Emily G. McDonald,Jonathon Milligan,Charles Frenette,Todd C. Lee,Todd C. Lee +5 more
TL;DR: Patients with continuous PPI use remained at elevated risk of CDI recurrence after adjustment for other independent predictors of recurrence, and it is suggested that the cessation of unnecessary P PI use should be considered at the time ofCDI diagnosis.
Journal ArticleDOI
Review: Hydroxychloroquine and chloroquine for treatment of SARS-CoV-2 (COVID-19)
Katelyn A Pastick,Elizabeth C Okafor,Fan Wang,Sarah M Lofgren,Caleb P Skipper,Melanie R. Nicol,Matthew F Pullen,Radha Rajasingham,Emily G. McDonald,Todd C. Lee,Ilan S. Schwartz,Lauren E. Kelly,Sylvain A. Lother,Oriol Mitjà,Emili Letang,Mahsa Abassi,David R. Boulware +16 more
TL;DR: A rapid narrative review and call for additional randomized controlled trial evidence prior to the widespread incorporation of hydroxychloroquine and chloroquine into national and international treatment guidelines are called for.