C
Charles Huggins
Researcher at University of Chicago
Publications - 168
Citations - 20484
Charles Huggins is an academic researcher from University of Chicago. The author has contributed to research in topics: Cancer & Prostate. The author has an hindex of 55, co-authored 168 publications receiving 19960 citations.
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Journal ArticleDOI
Induction of Adrenal Damage and Cancer with Metabolites of 7,12-Dimethylbenz(a)Anthracene
Two principles in endocrine therapy of cancers: hormone-deprival and hormone-interference.
TL;DR: In this article, two opposite sorts of change of the hormonal status can induce regression of such cancers: (a) deprivation of essential hormones; (b) hormone interference with large amounts of critical compounds.
Journal ArticleDOI
Changes in outlying bone marrow accompanying a local increase of temperature within physiological limits.
Charles Huggins,B. H. Blocksom +1 more
TL;DR: The evidence warrants the opinion that the cause of improvement is thermal, and in some experiments, blood cell formation was increasing while the heat was adversely affecting the testis, and the experiments permit construction of a general theory of fat distribution in bone marrow.
Journal ArticleDOI
Formation of bone marrow in fibroblast-transformation ossicles
A. H. Reddi,Charles Huggins +1 more
TL;DR: The genesis of hemopoietic bone marrow was studied in matrix-induced transformation plaques and ossicles in subcutaneous spaces of thorax and abdomen of rat and incorporation of 59-Fe into heme provided a sensitive quantitative assay for hemopOiesis.
Journal Article
Two Principles in Endocrine Therapy of Cancers: Hormone Deprival and Hormone Interference
TL;DR: Hormones are of crucial significance for growth of 7 hormone-dependent cancers of man and the animals and two opposite sorts of change of the hormonal status can induce regression of such cancers.