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Showing papers by "Charles J. Dimitroff published in 2011"

Journal Article•DOI•
Peracetylated 4-Fluoro-glucosamine Reduces the Content and Repertoire of N- and O-Glycans without Direct Incorporation

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Steven R. Barthel1, Steven R. Barthel2, Aristotelis Antonopoulos3, Filiberto Cedeno-Laurent1, Filiberto Cedeno-Laurent2, Lana Schaffer4, Gilberto E. Hernandez4, Shilpa A. Patil5, Simon J. North3, Anne Dell3, Khushi L. Matta6, Sriram Neelamegham5, Stuart M. Haslam3, Charles J. Dimitroff2, Charles J. Dimitroff1 •
Harvard University1, Brigham and Women's Hospital2, Imperial College London3, Scripps Research Institute4, State University of New York System5, Roswell Park Cancer Institute6
17 Jun 2011-Journal of Biological Chemistry
TL;DR: Data show that Gal-1 and E-selectin ligand reduction by 4-F-GlcNAc is not caused by direct 4- F-GlCNAc glycan incorporation and consequent chain termination but rather by interference with UDP-Gl cNAc synthesis.

60 citations