The term photonic crystals appears because of the analogy between electron waves in crystals and the light waves in artificial periodic dielectric structures. During the recent years the investigation of one-, two-and three-dimensional periodic structures has attracted a widespread attention of the world optics community because of great potentiality of such structures in advanced applied optical fields. The interest in periodic structures has been stimulated by the fast development of semiconductor technology that now allows the fabrication of artificial structures, whose period is comparable with the wavelength of light in the visible and infrared ranges.

http://ieeexplore.ieee.org/iel5/6354/16969/00781867.pdf

Photonic crystals

Fundamental and applied research in chemistry and biology benefits from opportunities provided by droplet-based microfluidic systems. These systems enable the miniaturization of reactions by compartmentalizing reactions in droplets of femoliter to microliter volumes. Compartmentalization in droplets provides rapid mixing of reagents, control of the timing of reactions on timescales from milliseconds to months, control of interfacial properties, and the ability to synthesize and transport solid reagents and products. Droplet-based microfluidics can help to enhance and accelerate chemical and biochemical screening, protein crystallization, enzymatic kinetics, and assays. Moreover, the control provided by droplets in microfluidic devices can lead to new scientific methods and insights.

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Reactions in Droplets in Microfluidic Channels

We describe devices in which optics and fluidics are used synergistically to synthesize novel functionalities. Fluidic replacement or modification leads to reconfigurable optical systems, whereas the implementation of optics through the microfluidic toolkit gives highly compact and integrated devices. We categorize optofluidics according to three broad categories of interactions: fluid–solid interfaces, purely fluidic interfaces and colloidal suspensions. We describe examples of optofluidic devices in each category.

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Developing optofluidic technology through the fusion of microfluidics and optics

This critical review summarizes developments in microfluidic platforms that enable the miniaturization, integration, automation and parallelization of (bio-)chemical assays (see S. Haeberle and R. Zengerle, Lab Chip, 2007, 7, 1094–1110, for an earlier review). In contrast to isolated application-specific solutions, a microfluidic platform provides a set of fluidic unit operations, which are designed for easy combination within a well-defined fabrication technology. This allows the easy, fast, and cost-efficient implementation of different application-specific (bio-)chemical processes. In our review we focus on recent developments from the last decade (2000s). We start with a brief introduction into technical advances, major market segments and promising applications. We continue with a detailed characterization of different microfluidic platforms, comprising a short definition, the functional principle, microfluidic unit operations, application examples as well as strengths and limitations of every platform. The microfluidic platforms in focus are lateral flow tests, linear actuated devices, pressure driven laminar flow, microfluidic large scale integration, segmented flow microfluidics, centrifugal microfluidics, electrokinetics, electrowetting, surface acoustic waves, and dedicated systems for massively parallel analysis. This review concludes with the attempt to provide a selection scheme for microfluidic platforms which is based on their characteristics according to key requirements of different applications and market segments. Applied selection criteria comprise portability, costs of instrument and disposability, sample throughput, number of parameters per sample, reagent consumption, precision, diversity of microfluidic unit operations and the flexibility in programming different liquid handling protocols (295 references).

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Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications

A photonic crystal fibre including a plurality of longitudinal holes (220), in which at least some of the holes have a different cross-sectional area in a first region (200) of the fibre, that region having been heat-treated after fabrication of the fibre, from their cross-sectional area in a second region of the fibre (190), wherein the optical properties of the fibre in the heat-treated region (200) are altered by virture of the change in cross-sectional area of holes (230) in that region (200).

Photonic crystal fibres

We demonstrate a high-throughput drop sorter for microfluidic devices that uses dielectrophoretic forces. Microelectrodes underneath a polydimethylsiloxane channel produce forces of more than 10nN on a water drop in an inert oil, resulting in sorting rates greater than 1.6kHz. We investigate the dependence of such forces on drop size and flow. Alternate designs with electrodes on either side of a symmetric channel Y junction provide refined control over droplet selection.

Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices

We present several applications of microstructured optical fibers and study their modal characteristics by using Bragg gratings inscribed into photosensitive core regions designed into the air-silica microstructure. The unique characteristics revealed in these studies enable a number of functionalities including tunability and enhanced nonlinearity that provide a platform for fiber device applications. We discuss experimental and numerical tools that allow characterization of the modes of the fibers.

Microstructured optical fiber devices.

We present a comprehensive study of mode propagation in a range of different air-silica microstructured fibers. The inscription of both Bragg and long-period gratings (LPGs) into the photosensitive core region of microstructured air-silica fibers has allowed us to generate complex transmission spectra from a range of fibers with various fill fractions and with increasing air-clad hole diameters. The spectral characteristics for typical air-hole geometry's are explained qualitatively and modeled using beam propagation simulations, where the numerical modeling corroborates the experimental measurements. Specifically, the data reveal the propagation of higher order leaky modes in fibers with periodically spaced air-holes, and relatively small air-fill fraction. And as the air-hole diameter increases, spectra show cladding modes defined solely by the inner air-clad region. We describe these measurements and corresponding simulations and discuss their implications for the understanding of such air-hole structures.

Cladding-mode-resonances in air-silica microstructure optical fibers

The ability to change the photonic band gap structure continuously and reversibly by modifying the index thermally allows the band gap features to be sensitively tuned, allowing for a thorough investigation of the various band gap guiding properties. Furthermore, it may be possible to use this type of band gap fiber as a tunable filter. Investigations of the dispersion properties of this fiber have been examined recently in our laboratory showing a change in dispersion > 10/sup 3/ ps/nm km across the band gap region suggesting that controlling the band gap position and width may also provide a sensitive method for tunable dispersion compensation.

Tunable photonic band gap fiber

We describe a class of active, tunable optical fiber that incorporates multiple microfluidic plugs into interior fiber microchannels. The propagation characteristics of certain optical modes of these fiber waveguides can be usefully manipulated by controlling the positions and optical properties of these plugs, using actuators and pumps formed on the fiber surface. These hybrid microfluidic/silica structures offer versatile tuning capabilities in a format that preserves the advantages of conventional, passive optical fiber. As an example, we report an all-fiber, narrowband filter, whose transmission wavelength and attenuation are independently adjustable via microfluidic tuning.

Charles Kerbage

Papers

Dielectrophoretic manipulation of drops for high-speed microfluidic sorting devices

Microstructured optical fiber devices.

Cladding-mode-resonances in air-silica microstructure optical fibers

Tunable photonic band gap fiber

Tunable microfluidic optical fiber