C
Charles S. Peskin
Researcher at Courant Institute of Mathematical Sciences
Publications - 7
Citations - 4331
Charles S. Peskin is an academic researcher from Courant Institute of Mathematical Sciences. The author has contributed to research in topics: Euchromatin & Organelle. The author has an hindex of 5, co-authored 7 publications receiving 3780 citations.
Papers
More filters
Journal ArticleDOI
The immersed boundary method
TL;DR: This paper is concerned with the mathematical structure of the immersed boundary (IB) method, which is intended for the computer simulation of fluid–structure interaction, especially in biological fluid dynamics.
Book
Modeling and Simulation in Medicine and the Life Sciences
TL;DR: The authors provides an introduction to a wide diversity of problems ranging from population phenomena to demographics, genetics, epidemics and dispersal; in physiological processes, including the circulation, gas exchange in the lungs, control of cell volume, the renal counter-current multiplier mechanism, and muscle mechanics; to mechanisms of neural control.
Journal ArticleDOI
Strong intracellular signal inactivation produces sharper and more robust signaling from cell membrane to nucleus.
Jingwei Ma,Myan Do,Mark A. Le Gros,Mark A. Le Gros,Charles S. Peskin,Carolyn A. Larabell,Carolyn A. Larabell,Yoichiro Mori,Samuel A. Isaacson +8 more
TL;DR: It is shown that signal inactivation sharpens signals, reducing variability in the arrival time at the nuclear membrane, and can also compensate for an observed slowdown in signal propagation induced by the presence of organelle barriers.
Journal ArticleDOI
The influence of spatial variation in chromatin density determined by X-ray tomograms on the time to find DNA binding sites.
Samuel A. Isaacson,Carolyn A. Larabell,Carolyn A. Larabell,Mark A. Le Gros,Mark A. Le Gros,David M. McQueen,Charles S. Peskin +6 more
TL;DR: The theory suggests that for binding sites in euchromatin there is an optimal level of volume exclusivity that balances a reduction in the volume searched in finding the binding site, with the height of effective potential barriers the protein must cross during the search process.
Posted ContentDOI
Strong intracellular signal inactivation produces sharper and more robust signaling from cell membrane to nucleus
Jingwei Ma,Myan Do,Mark A. Le Gros,Mark A. Le Gros,Charles S. Peskin,Carolyn A. Larabell,Carolyn A. Larabell,Yoichiro Mori,Samuel A. Isaacson +8 more
TL;DR: It is shown that signal inactivation sharpens signals, reducing variability in the arrival time at the nuclear membrane, and can also compensate for an observed slowdown in signal propagation induced by the presence of organelle barriers.