C
Charlotte De Bleye
Researcher at University of Liège
Publications - 27
Citations - 256
Charlotte De Bleye is an academic researcher from University of Liège. The author has contributed to research in topics: Raman spectroscopy & Hyperspectral imaging. The author has an hindex of 6, co-authored 27 publications receiving 147 citations.
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Journal ArticleDOI
A new criterion to assess distributional homogeneity in hyperspectral images of solid pharmaceutical dosage forms.
Pierre-Yves Sacre,Pierre Lebrun,Pierre-François Chavez,Charlotte De Bleye,Lauranne Netchacovitch,Eric Rozet,Régis Klinkenberg,Bruno Streel,Philippe Hubert,Eric Ziemons +9 more
TL;DR: Distributional Homogeneity Index (DHI) methodology appears to be a suitable tool for the analysis of homogeneity of distribution maps even without calibration during formulation development.
Journal ArticleDOI
Optimization of a pharmaceutical tablet formulation based on a design space approach and using vibrational spectroscopy as PAT tool.
Pierre-François Chavez,Pierre Lebrun,Pierre-Yves Sacre,Charlotte De Bleye,Lauranne Netchacovitch,Serge Cuypers,Jérôme Mantanus,Henri Motte,Martin Alexander Schubert,Brigitte Evrard,Philippe Hubert,Eric Ziemons +11 more
TL;DR: A design space approach supported by NIR and Raman spectroscopy was able to define a blend that complies with the target product profile with a quantified guarantee or risk.
Journal ArticleDOI
Active content determination of pharmaceutical tablets using near infrared spectroscopy as Process Analytical Technology tool
Pierre-François Chavez,Pierre-Yves Sacre,Charlotte De Bleye,Lauranne Netchacovitch,Jérôme Mantanus,Henri Motte,Martin Alexander Schubert,Philippe Hubert,Eric Ziemons +8 more
TL;DR: The NIR method based on the transmission mode was successfully used to monitor at-line the tablet active content during the tableting process, providing better insight of the API content during a process, thoroughly compliant with the Quality by Design (QbD) concept.
Journal ArticleDOI
From near-infrared and Raman to surface-enhanced Raman spectroscopy: progress, limitations and perspectives in bioanalysis.
Elodie Dumont,Charlotte De Bleye,Pierre-Yves Sacre,Lauranne Netchacovitch,Philippe Hubert,Eric Ziemons +5 more
TL;DR: The strengths and weaknesses of near-infrared, Raman and mainly surface-enhanced Raman spectroscopy and SERS will be highlighted with a focus on recent progress.
Journal ArticleDOI
New perspective for the in-field analysis of cannabis samples using handheld near-infrared spectroscopy: A case study focusing on the determination of Δ9-tetrahydrocannabinol.
Riccardo Deidda,Florentin Coppey,Dhouha Damergi,Cédric Schelling,Laureen Coic,Jean-Luc Veuthey,Pierre-Yves Sacre,Charlotte De Bleye,Philippe Hubert,Pierre Esseiva,Eric Ziemons +10 more
TL;DR: In this paper, the authors explored the feasibility of applying near-infrared (NIR) spectroscopy for the quantitative analysis of Δ9-tetrahydrocannabinol (THC) in cannabis products using handheld devices.