C
Charlotte H. W. Wijers
Researcher at Radboud University Nijmegen
Publications - 22
Citations - 631
Charlotte H. W. Wijers is an academic researcher from Radboud University Nijmegen. The author has contributed to research in topics: Population & VACTERL association. The author has an hindex of 12, co-authored 20 publications receiving 511 citations. Previous affiliations of Charlotte H. W. Wijers include Radboud University Nijmegen Medical Centre.
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Journal ArticleDOI
Whole-exome resequencing reveals recessive mutations in TRAP1 in individuals with CAKUT and VACTERL association
Pawaree Saisawat,Stefan Kohl,Alina C. Hilger,Alina C. Hilger,Daw Yang Hwang,Heon Yung Gee,Gabriel C. Dworschak,Gabriel C. Dworschak,Velibor Tasic,Tracie Pennimpede,Sivakumar Natarajan,Ethan D. Sperry,Danilo Swann Matassa,Natasa Stajic,Radovan Bogdanovic,Ivo de Blaauw,Carlo Marcelis,Charlotte H. W. Wijers,Enrika Bartels,Eberhard Schmiedeke,Dominik Schmidt,Dominik Schmidt,Stefanie Märzheuser,Sabine Grasshoff-Derr,Stefan Holland-Cunz,Michael Ludwig,Markus M. Nöthen,Markus Draaken,Erwin Brosens,Hugo A. Heij,Dick Tibboel,Bernhard G. Herrmann,Benjamin D. Solomon,Annelies de Klein,Iris A.L.M. van Rooij,Franca Esposito,Heiko Reutter,Heiko Reutter,Friedhelm Hildebrandt,Friedhelm Hildebrandt +39 more
TL;DR: In this article, the TNF receptor-associated protein 1 (TRAP1) was identified as highly likely causing CAKUT or VACTERL association in two families.
Journal ArticleDOI
Maternal and paternal risk factors for anorectal malformations: a Dutch case-control study.
Iris A.L.M. van Rooij,Charlotte H. W. Wijers,Paul N.M.A. Rieu,Hester S. Hendriks,Marijn M. Brouwers,Nine V A M Knoers,Ivo de Blaauw,Nel Roeleveld +7 more
TL;DR: Potential risk factors for ARM, including fever during pregnancy, maternal overweight, use of multivitamins, paternal smoking, and occupational exposures, but a familial component seems important as well are revealed.
Journal ArticleDOI
Research perspectives in the etiology of congenital anorectal malformations using data of the International Consortium on Anorectal Malformations: evidence for risk factors across different populations
Charlotte H. W. Wijers,Ivo de Blaauw,Carlo Marcelis,Rene M. H. Wijnen,Han G. Brunner,Paola Midrio,Piergiorgio Gamba,Maurizio Clementi,Ekkehart Jenetzky,Nadine Zwink,Heiko Reutter,Enrika Bartels,Sabine Grasshoff-Derr,Stefan Holland-Cunz,Stuart Hosie,Stefanie Märzheuser,Eberhard Schmiedeke,Célia Crétolle,Sabine Sarnacki,Marc A. Levitt,Marc A. Levitt,Nine V A M Knoers,Nel Roeleveld,Iris A.L.M. van Rooij +23 more
TL;DR: First results show that both genetic and environmental factors may contribute to the multifactorial etiology of ARM, ultimately resulting in better genetic counseling, improved therapies, and primary prevention.
Journal ArticleDOI
Genetic and nongenetic etiology of nonsyndromic anorectal malformations: a systematic review.
Charlotte H. W. Wijers,Iris A.L.M. van Rooij,Carlo Marcelis,Han G. Brunner,Ivo de Blaauw,Nel Roeleveld +5 more
TL;DR: In future studies, large cohorts of patients with ARM from national and international collaborations are needed to acquire new hypotheses and knowledge through hypothesis-generating approaches to conclude with unifying hypotheses and directions for future research.
Journal ArticleDOI
Maternal risk factors involved in specific congenital anomalies of the kidney and urinary tract: A case-control study.
Sander Groen In 't Woud,Kirsten Y. Renkema,Michiel F. Schreuder,Charlotte H. W. Wijers,Loes F.M. van der Zanden,Nine V A M Knoers,Wout F.J. Feitz,Ernie M.H.F. Bongers,Nel Roeleveld,Nel Roeleveld,Iris A.L.M. van Rooij +10 more
TL;DR: Use of folic acid only seems to be counterproductive for prevention of CAKUT, in contrast to multivitamin use, which stress the importance of separate analyses for each phenotype.