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Benjamin D. Solomon
Researcher at National Institutes of Health
Publications - 151
Citations - 6821
Benjamin D. Solomon is an academic researcher from National Institutes of Health. The author has contributed to research in topics: VACTERL association & Holoprosencephaly. The author has an hindex of 39, co-authored 143 publications receiving 5189 citations. Previous affiliations of Benjamin D. Solomon include Johns Hopkins University School of Medicine & Inova Health System.
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Journal ArticleDOI
A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity.
Angkana T. Huang,Bernardo García-Carreras,Matthew D. Hitchings,Bingyi Yang,Leah C. Katzelnick,Susan M Rattigan,Brooke A. Borgert,Carlos A. Moreno,Benjamin D. Solomon,Luke Trimmer-Smith,Veronique Etienne,Isabel Rodriguez-Barraquer,Justin Lessler,Henrik Salje,Henrik Salje,Henrik Salje,Donald S. Burke,Amy Wesolowski,Derek A. T. Cummings +18 more
TL;DR: While further studies of SARS-CoV-2 are necessary to determine immune responses, evidence from other coronaviruses can provide clues and guide future research.
Journal ArticleDOI
Sequencing Chromosomal Abnormalities Reveals Neurodevelopmental Loci that Confer Risk across Diagnostic Boundaries
Michael E. Talkowski,Jill A. Rosenfeld,Ian Blumenthal,Vamsee Pillalamarri,Colby Chiang,Adrian Heilbut,Carl Ernst,Carrie Hanscom,Elizabeth J. Rossin,Elizabeth J. Rossin,Amelia M. Lindgren,Shahrin Pereira,Douglas M. Ruderfer,Douglas M. Ruderfer,Andrew Kirby,Andrew Kirby,Stephan Ripke,Stephan Ripke,David J. Harris,Ji Hyun Lee,Kyungsoo Ha,Hyung Goo Kim,Benjamin D. Solomon,Andrea L. Gropman,Andrea L. Gropman,Diane Lucente,Katherine B. Sims,Toshiro K. Ohsumi,Mark L. Borowsky,Stephanie Loranger,Bradley J. Quade,Kasper Lage,Judith H. Miles,Bai-Lin Wu,Bai-Lin Wu,Bai-Lin Wu,Yiping Shen,Benjamin M. Neale,Benjamin M. Neale,Lisa G. Shaffer,Mark J. Daly,Cynthia C. Morton,Cynthia C. Morton,Cynthia C. Morton,James F. Gusella +44 more
TL;DR: The findings suggest a polygenic risk model of autism and reveal that some neurodevelopmental genes are sensitive to perturbation by multiple mutational mechanisms, leading to variable phenotypic outcomes that manifest at different life stages.
Journal ArticleDOI
Somatic Mutations in UBA1 and Severe Adult-Onset Autoinflammatory Disease.
David B. Beck,Marcela A. Ferrada,Keith A. Sikora,Amanda K. Ombrello,Jason C. Collins,Wuhong Pei,Nicholas Balanda,Daron L. Ross,Daniela Ospina Cardona,Zhijie Wu,Bhavisha A Patel,Kalpana Manthiram,Emma M. Groarke,Fernanda Gutierrez-Rodrigues,Patrycja Hoffmann,Sofia Rosenzweig,Shuichiro Nakabo,Laura W. Dillon,Christopher S. Hourigan,Wanxia L. Tsai,Sarthak Gupta,Carmelo Carmona-Rivera,Anthony J. Asmar,Lisha Xu,Hirotsugu Oda,Wendy Goodspeed,Karyl S. Barron,Michele Nehrebecky,Anne Jones,Ryan S. Laird,Natalie Deuitch,Dorota Rowczenio,Emily Rominger,Kristina V. Wells,Chyi-Chia Richard Lee,Weixin Wang,Megan Trick,James C. Mullikin,Gustaf Wigerblad,Stephen R. Brooks,Stefania Dell'Orso,Zuoming Deng,Jae Jin Chae,Alina Dulau-Florea,May Christine V. Malicdan,Danica Novacic,Robert A. Colbert,Mariana J. Kaplan,Massimo Gadina,Sinisa Savic,Helen J. Lachmann,Mones Abu-Asab,Benjamin D. Solomon,Kyle Retterer,William A. Gahl,Shawn M. Burgess,Ivona Aksentijevich,Neal S. Young,Katherine R. Calvo,Achim Werner,Daniel L. Kastner,Peter C. Grayson +61 more
TL;DR: Using a genotype-driven approach, this disorder is identified that connects seemingly unrelated adult-onset inflammatory syndromes and is named the VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome.
Journal ArticleDOI
VACTERL/VATER Association
TL;DR: The management of patients with VACTERL/VATER association typically centers around surgical correction of the specific congenital anomalies in the immediate postnatal period, followed by long-term medical management of sequelae of the congenital malformations.
Posted ContentDOI
A systematic review of antibody mediated immunity to coronaviruses: Antibody kinetics, correlates of protection, and association of antibody responses with severity of disease
Angkana T. Huang,Bernardo García-Carreras,Matthew D. Hitchings,Bingyi Yang,Leah C. Katzelnick,Susan M Rattigan,Brooke A. Borgert,Carlos A. Moreno,Benjamin D. Solomon,Isabel Rodriguez-Barraquer,Justin Lessler,Henrik Salje,Donald S. Burke,Amy Wesolowski,Derek A. T. Cummings +14 more
TL;DR: While studies of SARS-CoV-2 are necessary to determine immune responses to it, evidence from other coronaviruses can provide clues and guide future research.