C
Charu Sharma
Researcher at Council of Scientific and Industrial Research
Publications - 31
Citations - 656
Charu Sharma is an academic researcher from Council of Scientific and Industrial Research. The author has contributed to research in topics: Vibrio cholerae & El Tor. The author has an hindex of 14, co-authored 24 publications receiving 606 citations. Previous affiliations of Charu Sharma include University of Virginia & Central Drug Research Institute.
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Journal ArticleDOI
Molecular Analysis of Non-O1, Non-O139 Vibrio cholerae Associated with an Unusual Upsurge in the Incidence of Cholera-Like Disease in Calcutta, India
Charu Sharma,M. Thungapathra,Arghyaprasun Ghosh,Asish K. Mukhopadhyay,A Basu,Rupak Mitra,Indira Basu,S. K. Bhattacharya,Toshio Shimada,T. Ramamurthy,Tae Takeda,Shinji Yamasaki,Yoshifumi Takeda,G. Balakrish Nair +13 more
TL;DR: Overall, there was an excellent correlation between the results of ribotyping, RFLP analysis of various genes, andPFGE, with strains belonging to a particular serogroup showing nearly identical restriction patterns and PFGE profiles.
Journal ArticleDOI
Molecular Characterization of Vibrio cholerae O1 Biotype El Tor Strains Isolated between 1992 and 1995 in Calcutta, India: Evidence for the Emergence of a New Clone of the El Tor Biotype
Charu Sharma,Gopinath Balakrish Nair,Mukhopadhyay Ak,S. K. Bhattacharya,R. K. Ghosh,A. N. Ghosh +5 more
TL;DR: These studies clearly showed that El Tor O1 strains, which displaced V. cholerae O139 in Calcutta, belonged to a new clone and suggested that there is a continuous genetic reassortment among El Tor strains of V.Cholera O1.
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Unique organization of the CTX genetic element in Vibrio cholerae O139 strains which reemerged in Calcutta, India, in September 1996.
Charu Sharma,Sankar Maiti,Asish K. Mukhopadhyay,A Basu,Indira Basu,Gopinath Balakrish Nair,R Mukhopadhyaya,Bhabatosh Das,Sudeshna Kar,R. K. Ghosh,Alip Ghosh +10 more
TL;DR: While the strains from this resurgence were indistinguishable from the earlier strains by ribotyping, the structure of the CTX genetic element present in the current O139 strains was found to be unconventional.
Journal ArticleDOI
Eis (enhanced intracellular survival) protein of Mycobacterium tuberculosis disturbs the cross regulation of T-cells.
Ravi K. Lella,Charu Sharma +1 more
TL;DR: Insight is gained into the biological role of Eis in the host, which indicates that immunity in response to Eis treatment is skewed away from a protective TH1 response and Eis disturbs the cross regulation of T-cells.
Journal ArticleDOI
Heterogeneity in the organization of the CTX genetic element in strains of Vibrio cholerae O139 Bengal isolated from Calcutta, India and Dhaka, Bangladesh and its possible link to the dissimilar incidence of O139 cholera in the two locales
A Basu,Asish K. Mukhopadhyay,Charu Sharma,Jeevan Jyot,Naveen Gupta,Amit Ghosh,S. K. Bhattacharya,Yoshifumi Takeda,A. S. G. Faruque,M. John Albert,G. Balakrish Nair +10 more
TL;DR: After a lapse of 33 months, Vibrio cholerae O139, the new serogroup associated with cholera, has re-emerged in Calcutta, India and has become the dominant serogroups causing cholERA from September 1996.