C
Charuhas Deshpande
Researcher at University of Pennsylvania
Publications - 65
Citations - 3446
Charuhas Deshpande is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Cancer & Lung cancer. The author has an hindex of 27, co-authored 61 publications receiving 2720 citations. Previous affiliations of Charuhas Deshpande include Rush University Medical Center & Hospital of the University of Pennsylvania.
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Journal ArticleDOI
Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer.
Evgeniy Eruslanov,Pratik Bhojnagarwala,Jon G. Quatromoni,Tom L. Stephen,Anjana Ranganathan,Charuhas Deshpande,Tatiana Akimova,Anil Vachani,Leslie A. Litzky,Wayne W. Hancock,Jose R. Conejo-Garcia,Michael Feldman,Steven M. Albelda,Sunil Singhal +13 more
TL;DR: It is demonstrated that in the earliest stages of lung cancer, TANs are not immunosuppressive, but rather stimulate T cell responses.
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Pulmonary Pathologic Findings of Fatal 2009 Pandemic Influenza A/H1N1 Viral Infections
James R. Gill,Zong-Mei Sheng,Susan F. Ely,Donald G. Guinee,Mary Beth Beasley,James Suh,Charuhas Deshpande,Daniel J. Mollura,David M. Morens,Mike Bray,William D. Travis,Jeffery K. Taubenberger +11 more
TL;DR: Preexisting obesity, cardiorespiratory diseases, and other comorbidities also were prominent findings among the decedents, similar to findings identified in past pandemics.
Journal ArticleDOI
Origin and Role of a Subset of Tumor-Associated Neutrophils with Antigen-Presenting Cell Features in Early-Stage Human Lung Cancer
Sunil Singhal,Sunil Singhal,Pratik Bhojnagarwala,Shaun O'Brien,Edmund K. Moon,Alfred L. Garfall,Abhishek Rao,Jon G. Quatromoni,Tom L. Stephen,Leslie A. Litzky,Charuhas Deshpande,Michael Feldman,Wayne W. Hancock,Wayne W. Hancock,Jose R. Conejo-Garcia,Steven M. Albelda,Evgeniy Eruslanov +16 more
TL;DR: A subset of TANs that exhibited characteristics of both neutrophils and antigen-presenting cells (APCs) in early-stage human lung cancer are identified, demonstrating the existence of a specialized TAN subset with anti-tumor capabilities in human cancer.
Journal ArticleDOI
Comprehensive histologic assessment helps to differentiate multiple lung primary nonsmall cell carcinomas from metastases.
Nicolas Girard,Charuhas Deshpande,Christopher Lau,David J. Finley,Valerie W. Rusch,William Pao,William D. Travis +6 more
TL;DR: Comprehensive histologic assessment is a powerful tool that seems to be a promising way to determine whether multiple lung adenocarcinomas or squamous cell carcinomas are metastatic or multiple primaries, which has great clinical implications for staging and therapeutic management of lung cancer patients with multiple tumors.
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Pembrolizumab After Completion of Locally Ablative Therapy for Oligometastatic Non–Small Cell Lung Cancer: A Phase 2 Trial
Joshua Bauml,Rosemarie Mick,Christine Ciunci,Charu Aggarwal,Christiana Davis,Tracey L. Evans,Charuhas Deshpande,Linda Miller,Pooja R. Patel,Evan W. Alley,Christina Knepley,Faith Mutale,Roger B. Cohen,Corey J. Langer +13 more
TL;DR: Pembrolizumab after LAT for oligometastatic NSCLC appears to improve progression-free survival with no reduction in quality of life, and this study was powered for comparison with historical data on the first efficacy end point.