E
Evgeniy Eruslanov
Researcher at University of Pennsylvania
Publications - 68
Citations - 6224
Evgeniy Eruslanov is an academic researcher from University of Pennsylvania. The author has contributed to research in topics: Immune system & Cancer. The author has an hindex of 34, co-authored 62 publications receiving 4751 citations. Previous affiliations of Evgeniy Eruslanov include Russian Academy & University of Florida.
Papers
More filters
Book ChapterDOI
Identification of ROS Using Oxidized DCFDA and Flow-Cytometry
TL;DR: 2'-7'-Dichlorodihydrofluorescein diacetate (DCFH-DA) is one of the most widely used techniques for directly measuring the redox state of a cell and can be used to follow changes in ROS over time.
Journal ArticleDOI
Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients
Thomas Condamine,George A. Dominguez,Je-In Youn,Andrew V. Kossenkov,Sridevi Mony,Kevin Alicea-Torres,Evgenii N. Tcyganov,Ayumi Hashimoto,Yulia Nefedova,Cindy Lin,Simona Partlova,Alfred L. Garfall,Dan T. Vogl,Xiaowei Xu,Stella C. Knight,George Malietzis,Gui Han Lee,Evgeniy Eruslanov,Steven M. Albelda,Xianwei Wang,Jawahar L. Mehta,Meenakshi Bewtra,Anil K. Rustgi,Neil Hockstein,Robert L Witt,Gregory A. Masters,Brian Nam,Denis Smirnov,Manuel A. Sepulveda,Dmitry I. Gabrilovich +29 more
TL;DR: A specific marker of human PMN-MDSC associated with ER stress and lipid metabolism is identified, which provides new insights into the biology and potential therapeutic targeting of these cells.
Journal ArticleDOI
Tumor-associated neutrophils stimulate T cell responses in early-stage human lung cancer.
Evgeniy Eruslanov,Pratik Bhojnagarwala,Jon G. Quatromoni,Tom L. Stephen,Anjana Ranganathan,Charuhas Deshpande,Tatiana Akimova,Anil Vachani,Leslie A. Litzky,Wayne W. Hancock,Jose R. Conejo-Garcia,Michael Feldman,Steven M. Albelda,Sunil Singhal +13 more
TL;DR: It is demonstrated that in the earliest stages of lung cancer, TANs are not immunosuppressive, but rather stimulate T cell responses.
Journal Article
Tumor-associated macrophages: function, phenotype, and link to prognosis in human lung cancer
TL;DR: The current understanding of how the tumor microenvironment takes advantage of macrophage plasticity to mold an immunosuppressive population, the phenotypic heterogeneity of TAMs, and their link to prognosis in human lung cancer are summarized.
Journal ArticleDOI
Reversal of myeloid cell-mediated immunosuppression in patients with metastatic renal cell carcinoma.
Sergei Kusmartsev,Zhen Su,Axel Heiser,Jens Dannull,Evgeniy Eruslanov,Hubert Kübler,Donna Yancey,Philip Dahm,Johannes Vieweg +8 more
TL;DR: The role of CD33 myeloid-derived suppressor cells (MDSC) in the regulation of T-cell responses in renal cell carcinoma patients is evaluated and the results may have significant implications regarding the future design of active immunotherapy protocols that may include differentiation agents.