C
Chee Wun How
Researcher at Monash University Malaysia Campus
Publications - 48
Citations - 1263
Chee Wun How is an academic researcher from Monash University Malaysia Campus. The author has contributed to research in topics: Apoptosis & Medicine. The author has an hindex of 18, co-authored 40 publications receiving 904 citations. Previous affiliations of Chee Wun How include University of Murcia & National University of Malaysia.
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Journal ArticleDOI
Zerumbone-loaded nanostructured lipid carriers: preparation, characterization, and antileukemic effect.
Heshu Sulaiman Rahman,Abdullah Rasedee,Chee Wun How,Ahmad Bustamam Abdul,Nazariah Allaudin Zeenathul,Hemn Hassan Othman,Mohamed Ibrahim Saeed,Swee Keong Yeap +7 more
TL;DR: Zerumbone-loaded nanostructured lipid carriers (ZER-NLC) have potential as a sustained-release drug carrier system for the treatment of leukemia, according to physicochemical properties.
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Tamoxifen-loaded nanostructured lipid carrier as a drug delivery system: characterization, stability assessment and cytotoxicity.
TL;DR: The development of a stable nanostructured lipid carrier (NLC) system as carrier for Tamoxifen and the first encouraging report on the in vitro effect of TAM-NLC against human and mouse mammary adenocarcinoma cell lines are reported.
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Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular administration.
Siddig Ibrahim Abdelwahab,Bassem Y. Sheikh,Manal Mohamed Elhassan Taha,Chee Wun How,Rasedee Abdullah,Umar Yagoub,Rashad El-Sunousi,Eltayeb E M Eid +7 more
TL;DR: NLCs could be a promising vehicle for the oral delivery of TQ and improve its gastroprotective properties, and inhibited the formation of ethanol-induced ulcers through the modulation of heat shock protein-70 (Hsp70).
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Thymoquinone-Loaded Nanostructured Lipid Carrier Exhibited Cytotoxicity towards Breast Cancer Cell Lines (MDA-MB-231 and MCF-7) and Cervical Cancer Cell Lines (HeLa and SiHa)
Wei Keat Ng,Latifah Saiful Yazan,Li Hua Yap,Wan Abd Ghani Wan Nor Hafiza,Chee Wun How,Rasedee Abdullah +5 more
TL;DR: Thymoquinone-loaded nanostructured lipid carrier TQ-NLC exhibited antiproliferative activity towards all the cell lines in a dose-dependent manner which was most cytotoxic towards MDA-MB-231 cells.
Journal ArticleDOI
Biomedical Properties of a Natural Dietary Plant Metabolite, Zerumbone, in Cancer Therapy and Chemoprevention Trials
Heshu Sulaiman Rahman,Abdullah Rasedee,Swee Keong Yeap,Hemn Hassan Othman,Max Stanley Chartrand,Farideh Namvar,Ahmad Bustamam Abdul,Chee Wun How +7 more
TL;DR: Much of the research outlined in this paper will serve as a foundation to explain ZER anticancer bioactivity, which will open the door for the development of strategies in the treatment of malignancies using ZER.