C
Chellan Kumarasamy
Researcher at University of Adelaide
Publications - 60
Citations - 536
Chellan Kumarasamy is an academic researcher from University of Adelaide. The author has contributed to research in topics: Meta-analysis & Cancer. The author has an hindex of 12, co-authored 51 publications receiving 381 citations. Previous affiliations of Chellan Kumarasamy include Charles Darwin University & SRM University.
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Journal ArticleDOI
Prognostic significance of blood inflammatory biomarkers NLR, PLR, and LMR in cancer-A protocol for systematic review and meta-analysis.
Chellan Kumarasamy,Shanthi Sabarimurugan,Royam Madhav Madurantakam,Kartik Lakhotiya,Suja Samiappan,Siddhratha Baxi,Ramesh Nachimuthu,Kodiveri Muthukaliannan Gothandam,Rama Jayaraj +8 more
TL;DR: This meta-analysis protocol examines the comparative utility of neutrophil-lymphocyte-ratio, platelet-ly mphocyte- ratio, and monocyte-lyymphocyte-Ratio as a simple, inexpensive, and effective method for cancer prognosis, in multiple cancers.
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Clinical Theragnostic Relationship between Drug-Resistance Specific miRNA Expressions, Chemotherapeutic Resistance, and Sensitivity in Breast Cancer: A Systematic Review and Meta-Analysis
Rama Jayaraj,Sankaranarayanan Gomathi Nayagam,Ananya S. Kar,Shubhangi Sathyakumar,Hina Mohammed,Maria Smiti,Shanthi Sabarimurugan,Chellan Kumarasamy,T Priyadharshini,Kodiveri Muthukaliannan Gothandam,N Ramesh,Ajay Gupta,Siddhartha Baxi,Suja Swamiappan,Sunil Krishnan +14 more
TL;DR: A comprehensive systematic review and meta-analysis on the role of miRNAs in influencing the chemoresistance and sensitivity of breast cancer suggests there are different mi RNAs involved in the regulation of chemores resistance through diverse drug genetic targets.
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Prognostic Value of miRNAs in Head and Neck Cancers: A Comprehensive Systematic and Meta-Analysis
Chellan Kumarasamy,Madurantakam Royam Madhav,Shanthi Sabarimurugan,Sunil Krishnan,Siddhartha Baxi,Ajay Gupta,Kodiveri Muthukaliannan Gothandam,Rama Jayaraj +7 more
TL;DR: Results indicate that miRNAs have potential clinical value as prognostic biomarkers in HNC, with miR-21, 125b, 34c-5p and 18a, in particular, showing great potential as progostic molecular markers.
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Systematic review and meta-analysis of prognostic microRNA biomarkers for survival outcome in nasopharyngeal carcinoma.
TL;DR: It is noted that the combined effect estimate of HR across multiple studies indicated that increased miRNA expression in NPC potentially leads to poor overall survival, but further large-scale prospective studies on the clinical significance of the miRNAs, with sizable cohorts are necessary in order to obtain conclusive results.
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MiRNA predictors of pancreatic cancer chemotherapeutic response: A systematic review and meta-analysis
Madhav Madurantakam Royam,Rithika Ramesh,Ritika Shanker,Shanthi Sabarimurugan,Chellan Kumarasamy,Nachimuthu Ramesh,Kodiveri Muthukalianan Gothandam,Siddharta Baxi,Ajay Gupta,Sunil Krishnan,Rama Jayaraj +10 more
TL;DR: The results highlight multiple miRNAs that have possible associations with modulation of chemotherapy response in pancreatic cancer patients and further studies are needed to discover the molecular mechanisms underlying these associations before they can be suggested for use as biomarkers of response to chemotherapeutic interventions in Pancic cancer.