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Chen-Hsiang Lee
Researcher at Chang Gung University
Publications - 61
Citations - 792
Chen-Hsiang Lee is an academic researcher from Chang Gung University. The author has contributed to research in topics: Medicine & Internal medicine. The author has an hindex of 14, co-authored 45 publications receiving 609 citations. Previous affiliations of Chen-Hsiang Lee include Memorial Hospital of South Bend.
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Treatment of ESBL-producing Klebsiella pneumoniae bacteraemia with carbapenems or flomoxef: a retrospective study and laboratory analysis of the isolates.
TL;DR: Flamoxef might be as clinically effective as a carbapenem in treating flomoxef-susceptible ESBL-KP bacteraemia.
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Collateral damage of flomoxef therapy: in vivo development of porin deficiency and acquisition of blaDHA-1 leading to ertapenem resistance in a clinical isolate of Klebsiella pneumoniae producing CTX-M-3 and SHV-5 β-lactamases
Chen-Hsiang Lee,Chishih Chu,Jien-Wei Liu,Yi-Shung Chen,Chiung-Jung Chiu,Lin-Hui Su,Lin-Hui Su +6 more
TL;DR: After flomoxef exposure, the in vivo acquisition of the plasmid-mediated blaDHA-1 gene has led to flomxef resistance in Lkp14, and the concomitant depletion of OmpK36 expression has resulted in a collateral effect of ertapenem resistance and diminished susceptibilities to imipenem and meropenem.
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Hypermucoviscosity associated with Klebsiella pneumoniae-mediated invasive syndrome: a prospective cross-sectional study in Taiwan.
Chen-Hsiang Lee,Jien-Wei Liu,Lin-Hui Su,Chun-Chih Chien,Chia-Chin Li,Kuender-D. Yang,Kuender-D. Yang +6 more
TL;DR: The HV phenotype of K. pneumoniae contributes to invasive syndrome and is a negative predictor for K. infections and pneumoniae acquisition of ESBLs.
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Antimicrobial effects of varied combinations of meropenem, sulbactam, and colistin on a multidrug-resistant Acinetobacter baumannii isolate that caused meningitis and bacteremia.
TL;DR: Combined use of COL with MEM and/or SUL may provide good therapeutic options, even though MEM and SUL are in vitro resistance to the MDRAB.
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Evaluation of Macrolide Resistance and Enhanced Molecular Typing of Treponema pallidum in Patients with Syphilis in Taiwan: a Prospective Multicenter Study
Hsiu Wu,Sui-Yuan Chang,Nan Yao Lee,Wen-Chi Huang,Bing-Ru Wu,Chia-Jui Yang,Shiou-Haur Liang,Chen-Hsiang Lee,Wen Chien Ko,Hsi-Hsun Lin,Yen-Hsu Chen,Wen-Chun Liu,Yi-Ching Su,Chia-Yin Hsieh,Pei-Ying Wu,Chien-Ching Hung +15 more
TL;DR: It is found that type 14 f/f was the most common T. pallidum strain in this multicenter study on syphilis in Taiwan and that none of the isolates exhibited 23S rRNA mutations causing resistance to macrolides.