Chen Minhu

TL;DR: It is concluded that publication of a single pooled global prevalence rate, which is easily calculated, would not be appropriate or contributory, and future studies should focus on regional and cross-cultural differences that are more likely to shed light on pathophysiology.

TL;DR: Silybin, a natural antioxidant, has been traditionally used against a variety of liver ailments to investigate its effect and the underlying mechanisms of action on non-alcoholic fatty liver in rats as discussed by the authors.

TL;DR: The results of this study suggest that the value of TPMT genotyping before thiopurine therapy is limited in Chinese patients with IBD, considering the low sensitivity of predicting leucopenia, and that phenotyping is a more cost-effective tool that can be successfully used in patients.

TL;DR: The results provide the evidence that rs11465788 may influence the susceptibility and clinical features of CD in Chinese population and Genotype-phenotypic interaction analysis showed that rs 11465788 is associated with nonstricturing and nonpenetrating disease behaviour in CD patients.

TL;DR: A 6-TGN level between 225 and 420 pmol/8 × 108 RBC could be a therapeutic window in patients receiving AZA therapy, and it could likely predict leucopenia in the initial 12 weeks of AZA Therapy and a reasonable chance of successful clinical response in CD patients.