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Cheng-Che E. Lan

Researcher at Kaohsiung Medical University

Publications -  90
Citations -  2781

Cheng-Che E. Lan is an academic researcher from Kaohsiung Medical University. The author has contributed to research in topics: Keratinocyte & Psoriasis. The author has an hindex of 23, co-authored 84 publications receiving 2172 citations. Previous affiliations of Cheng-Che E. Lan include Kaohsiung Medical University Chung-Ho Memorial Hospital.

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Helium-neon laser irradiation stimulates cell proliferation through photostimulatory effects in mitochondria.

TL;DR: Results suggest that He-Ne irradiation elicits photostimulatory effects in mitochondria processes, which involve JNK/AP-1 activation and enhanced growth factor release, and ultimately lead to A2058 cell proliferation.
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Rates of cutaneous metastases from different internal malignancies: experience from a Taiwanese medical center.

TL;DR: The mechanisms responsible for the cutaneous metastatic ability of certain malignancies likely involve factors other than chemokine receptors CCR10 and CXCR4, because their expressions by tumor cells are neither necessary nor sufficient for the formation of skin metastases.
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High-Glucose Environment Enhanced Oxidative Stress and Increased Interleukin-8 Secretion From Keratinocytes: New Insights Into Impaired Diabetic Wound Healing

TL;DR: IL-8 production and neutrophil infiltration are increased in a high-glucose environment due to elevated ROS level and contributed to impaired wound healing in diabetic skin, and targeting these dysfunctions may present novel therapeutic approaches.
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Neutrophil extracellular trap formation is increased in psoriasis and induces human β-defensin-2 production in epidermal keratinocytes.

TL;DR: Net formation is increased in peripheral blood and lesional skin of psoriasis patients and correlates with disease severity, and NET-induced HBD-2 production may provide a novel mechanism for the decreased susceptibility of Psoriasis plaques to microbial infections.