Cheng-Sheng Huang

TL;DR: Dose-response characterization of the photonic crystal antibody microarrays shows the capability to detect common cancer biomarkers in the <2 pg/mL concentration range within a mixed sample.

TL;DR: A Photonic Crystal surface fabricated upon a quartz substrate using nanoimprint lithography has been demonstrated with a signal enhancement factor as high as 7500x for the detection of LD-700 dye spin-coated upon the PC.

TL;DR: In this paper, a linear variable filter based on a guidedmode resonance filter (GMRF) with gradient grating periods was first fabricated through nanoreplica molding on a plastic substrate, which was followed by the deposition of a thin TiO2 film.

TL;DR: A detection instrument is demonstrated that supports fluorescence and label-free imaging modalities, with the ability to optimize the fluorescence enhancement factor on a pixel-by-pixel basis throughout the microarray using an angle-scanning approach for the excitation laser that automatically compensates for variability in surface chemistry density and capture spot density.

TL;DR: In this article, a guided-mode resonance (GMR) filter mounted on a linear charge-coupled device (CCD) was used to detect a single wavelength with a resolution of 0.5 nm.