Chengde Gao

TL;DR: A comprehensive review of the state of the art of bone biomaterials and their interactions with stem cells is presented and the promising seed stem cells for bone repair are summarized, and their interaction mechanisms are discussed in detail.

TL;DR: The strategy reported here is to blend a biodegradable polymer with PEEK and β‐TCP to fabricate multi‐material scaffolds via selective laser sintering (SLS), and large numbers of caverns form on the membrane with the degradation of PLLA, enabling direct contact between β‐ TCP and body fluid, and allowing for their ion‐exchange.

TL;DR: The types and characters of bioactive ceramics, the fabrication methods for nanostructure and hierarchically porous structure, typical toughness methods for ceramic scaffold and corresponding mechanisms such as fiber toughness, whisker toughness and particle toughness are summarized.

TL;DR: This review presents a comprehensive overview of the developments and applications of LDNs in bioactive ceramics, including the newly-developed fabrication methods for LDNs/ceramic composites, the reinforcing mechanisms and the in vitro and in vivo performance ofLDNs.

TL;DR: The use of graphene is reported to improve the mechanical properties of nano-58S bioactive glass for bone repair and regeneration and suggests a great potential of graphene/nano- 58S composite scaffold for bone tissue engineering applications.