C
Chengfeng Zhao
Researcher at Marshfield Clinic
Publications - 6
Citations - 1160
Chengfeng Zhao is an academic researcher from Marshfield Clinic. The author has contributed to research in topics: Locus (genetics) & Genetic linkage. The author has an hindex of 6, co-authored 6 publications receiving 1105 citations.
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Journal ArticleDOI
Human Diallelic Insertion/Deletion Polymorphisms
TL;DR: The identification and characterization of 2,000 human diallelic insertion/deletion polymorphisms (indels) distributed throughout the human genome found that new alleles were generally lower in frequency than old alleles.
Journal ArticleDOI
Homozygous wnt3 mutation causes tetra-amelia in a large consanguineous family
Stephan Niemann,Chengfeng Zhao,Filon Pascu,Ulrich Stahl,Ute Aulepp,Lee Niswander,James L. Weber,Ulrich Müller +7 more
TL;DR: The identification of a WNT3 mutation in tetra-amelia indicates that Wnt3 is required at the earliest stages of human limb formation and for craniofacial and urogenital development.
Journal ArticleDOI
Comparison of human genetic and sequence-based physical maps
Adong Yu,Chengfeng Zhao,Ying Fan,Wonhee Jang,Andrew J. Mungall,Panos Deloukas,Anne S. Olsen,Norman A. Doggett,Nader Ghebranious,Karl W. Broman,James L. Weber +10 more
TL;DR: Estimates of female, male and sex-average recombination rates for about 60% of the genome are described and several chromosomal regions up to 6 Mb in length are identified with particularly low (deserts) or high (jungles) recombination rate.
Journal ArticleDOI
Assignment of two loci for autosomal dominant adolescent idiopathic scoliosis to chromosomes 9q31.2-q34.2 and 17q25.3-qtel
Louise Ocaka,Chengfeng Zhao,Johanna A Reed,Neil D. Ebenezer,Glen Brice,Timothy Morley,Min Mehta,John O’Dowd,James L Weber,Alison J. Hardcastle,Anne H. Child +10 more
TL;DR: A common locus for AIS in the British population is reported, mapping to a refined interval on chromosome 9q31.2 and defines a novel AIS locus on chromosome 17q25.3-qtel.
Journal ArticleDOI
A novel locus for adolescent idiopathic scoliosis on chromosome 12p.
Cathleen L. Raggio,Philip F. Giampietro,Philip F. Giampietro,Seth E. Dobrin,Chengfeng Zhao,Donna Dorshorst,Nader Ghebranious,James L. Weber,Robert D. Blank +8 more
TL;DR: This study is the first to find evidence of an AIS susceptibility locus on chromosome 12, and detects QTLs on multiple chromosomes in this and other studies demonstrate that the condition is genetically heterogeneous.