C
Cheryl L. Mayo
Researcher at University of Maryland, Baltimore
Publications - 16
Citations - 1867
Cheryl L. Mayo is an academic researcher from University of Maryland, Baltimore. The author has contributed to research in topics: Gene & Candidate gene. The author has an hindex of 11, co-authored 16 publications receiving 1566 citations. Previous affiliations of Cheryl L. Mayo include University of Maryland, College Park.
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Journal ArticleDOI
NMDAR inhibition-independent antidepressant actions of ketamine metabolites
Panos Zanos,Ruin Moaddel,Patrick J. Morris,Polymnia Georgiou,Jonathan Fischell,Greg I. Elmer,Manickavasagom Alkondon,Peixiong Yuan,Heather J. Pribut,Nagendra Singh,Katina Sourou Sylvestre Dossou,Yuhong Fang,Xi Ping Huang,Cheryl L. Mayo,Irving W. Wainer,Edson X. Albuquerque,Scott M. Thompson,Craig J. Thomas,Carlos A. Zarate,Todd D. Gould +19 more
TL;DR: It is shown that the metabolism of (R,S)-ketamine to (2S,6S;2R,6R)-hydroxynorketamine (HNK) is essential for its antidepressant effects, and that the HNK enantiomer exerts behavioural, electroencephalographic, electrophysiological and cellular antidepressant-related actions in mice.
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Prenatal exposure to a repeated variable stress paradigm elicits behavioral and neuroendocrinological changes in the adult offspring: potential relevance to schizophrenia.
James I. Koenig,Gregory I. Elmer,Paul D. Shepard,Paul R. Lee,Cheryl L. Mayo,Brian Joy,Ericka Hercher,Dana L. Brady +7 more
TL;DR: The findings suggest that prenatal stress exposure significantly changed many facets of adult rat behavior and may be useful to learn more about some aspects of the pathophysiology of schizophrenia.
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SEE locomotor behavior test discriminates C57BL/6J and DBA/2J mouse inbred strains across laboratories and protocol conditions.
TL;DR: This study explores the hypothesis that automated tests can be designed to quantify ethologically relevant behavior patterns that more readily characterize heritable and replicable phenotypes and suggests that well-designed tests may considerably enhance replicability across laboratories.
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Combined Application of Behavior Genetics and Microarray Analysis to Identify Regional Expression Themes and Gene–Behavior Associations
Noah E. Letwin,Neri Kafkafi,Yoav Benjamini,Cheryl L. Mayo,Bryan C. Frank,Troung Luu,Norman H. Lee,Greg I. Elmer +7 more
TL;DR: Gene expression signatures were generated for the prefrontal cortex, ventral striatum, temporal lobe, periaqueductal gray, and cerebellum in eight inbred strains from priority group A of the Mouse Phenome Project, revealing both functional and structural specialization of particular brain regions.
Journal ArticleDOI
Darting behavior: a quantitative movement pattern designed for discrimination and replicability in mouse locomotor behavior.
Neri Kafkafi,Neri Kafkafi,Michal Pagis,Dina Lipkind,Cheryl L. Mayo,Yoav Bemjamini,Ilan Golani,Gregory I. Elmer +7 more
TL;DR: The replicability of darting behavior was confirmed in additional experiments distinct from those used for its design, and the strategy leading to the darting measure may be used to develop additional discriminative and replicable endpoints of open-field behavior.