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Chih-Hsien Lee

Researcher at Chung Yuan Christian University

Publications -  14
Citations -  1023

Chih-Hsien Lee is an academic researcher from Chung Yuan Christian University. The author has contributed to research in topics: Nanoclusters & Microbubbles. The author has an hindex of 7, co-authored 14 publications receiving 948 citations.

Papers
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Journal ArticleDOI

Synthesis, Characterization, and Bioconjugation of Fluorescent Gold Nanoclusters toward Biological Labeling Applications

TL;DR: Synthesis of ultrasmall water-soluble fluorescent gold nanoclusters has a decent quantum yield, high colloidal stability, and can be readily conjugated with biological molecules.
Journal ArticleDOI

Fluorescent gold nanoclusters as a biocompatible marker for in vitro and in vivo tracking of endothelial cells.

TL;DR: In vivo study using hindlimb ischemic mice with an intramuscular injection of FANC-labeled human EPC showed that the cells preserved an angiogenic potential and exhibited traceable signals after 21 days, demonstrating that FANC is a promising biocompatible fluorescent probe.

Synthesis of Fluorescent Metallic Nanoclusters toward Biomedical Application: Recent Progress and Present Challenges

TL;DR: In this review, a new class of fluorescent labels by biocognition molecules to fluorescent noble-metal nanoclusters such as Au and Ag are produced, which are more biocompatible and stable against photobleaching compared with organic dyes and are ideal fluorophores for multicolor and multiplexing applications in biomedical engineering and molecular biotechnology.
Journal ArticleDOI

Application of Gold in Biomedicine: Past, Present and Future

TL;DR: F fluorescent gold nanoclusters (FANCs) are developed that contain gold nanoparticles with a core dimension in vitro and in vivo tracking of endothelial and endothelial progenitor cells and may also have novel chemical properties involved in regulation of endothelium cell function.
Patent

Fluorescent Gold Nanocluster and Method for Forming the Same

TL;DR: In this paper, a fluorescent gold nanocluster, comprising of a dihydrolipoic acid ligand (DHLA) on the surface thereof, was shown to generate fluorescence by the interaction between the DHLA and the nanocuster.