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Ching-Quo Wong
Researcher at La Roche College
Publications - 10
Citations - 1361
Ching-Quo Wong is an academic researcher from La Roche College. The author has contributed to research in topics: Mutation frequency & Ames test. The author has an hindex of 9, co-authored 10 publications receiving 1350 citations.
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Journal Article
Inhibitory Effect of Curcumin, Chlorogenic Acid, Caffeic Acid, and Ferulic Acid on Tumor Promotion in Mouse Skin by 12-O-Tetradecanoylphorbol-13-acetate
TL;DR: The effects of topically applied curcumin, chlorogenic acid, caffeic acid, or ferulic acid on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced epidermal ornithine decarboxylase activity, epidersmal DNA synthesis, and the promotion of skin tumors were evaluated in female CD-1 mice.
Journal Article
Inhibitory effect of green tea in the drinking water on tumorigenesis by ultraviolet light and 12-O-tetradecanoylphorbol-13-acetate in the skin of SKH-1 mice.
Zhi Yuan Wang,Mou-Tuan Huang,Thomas Ferraro,Ching-Quo Wong,You-Rong Lou,Kenneth R. Reuhl,Michael J. Iatropoulos,Chung S. Yang,Allan H. Conney +8 more
TL;DR: Treatment of the animals with the green tea extract not only decreased the number of skin tumors but also decreased substantially the size of the tumors.
Journal Article
Dose-dependent Differences in the Profile of Mutations Induced by (+)-7R,8S-Dihydroxy-9S,10R-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene in the Coding Region of the Hypoxanthine (Guanine) Phosphoribosyltransferase Gene in Chinese Hamster V-79 Cells
S.-J. C. Wei,R. L. Chang,N. Bhachech,Xiao Xing Cui,K. A. Merkler,Ching-Quo Wong,E. Hennig,Haruhiko Yagi,D M Jerina,Allan H. Conney +9 more
TL;DR: Results indicated that decreasing the dose of (+)-BPDE decreased the proportion of mutations at GC base pairs and increased the proportion at AT base pairs, and dose-dependent differences in (+)- BPDE-induced exon deletions and hot spots for base substitutions at GC and AT base Pair were indicated.
Journal ArticleDOI
Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,10-epoxide enantiomers with high and low carcinogenic activity
S.-J. C. Wei,Richard L. Chang,E. Hennig,Xiao Xing Cui,K. A. Merkler,Ching-Quo Wong,Haruhiko Yagi,Donald M. Jerina,Allan H. Conney +8 more
TL;DR: There was a trend towards an increase in the proportion of mutations at AT base pairs when the dose of (-)-BPDE was decreased, but this trend was not statistically significant and the data indicated no dose-dependent differences in the kinds of base substitutions or exon deletions in cDNAs induced by (-)- BPDE.
Journal Article
Large Bowel Carcinogenesis in Mice and Rats by Several Intrarectal Doses of Methylnitrosourea and Negative Effect of Nitrite Plus Methylurea
TL;DR: The carcinogenic effect of several dose levels and regimens of an aqueous solution of N-methyl-N-nitrosourea (MNU) administered intrarectally to mice and rats is reported in this paper.