C
Chris Englund
Researcher at University of Washington
Publications - 15
Citations - 3653
Chris Englund is an academic researcher from University of Washington. The author has contributed to research in topics: Neurogenesis & TBR1. The author has an hindex of 14, co-authored 15 publications receiving 3405 citations. Previous affiliations of Chris Englund include Seattle Children's & Harborview Medical Center.
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Journal ArticleDOI
Pax6, Tbr2, and Tbr1 Are Expressed Sequentially by Radial Glia, Intermediate Progenitor Cells, and Postmitotic Neurons in Developing Neocortex
Chris Englund,Andy Fink,Charmaine Lau,Diane Pham,Ray A. M. Daza,Alessandro Bulfone,Tom Kowalczyk,Robert F. Hevner +7 more
TL;DR: It is shown that the transition from radial glia to intermediate progenitor cell is associated with upregulation of Tbr2, a T-domain transcription factor, and downregulation of Pax6, a homeodomain transcription factor.
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Transcription factors in glutamatergic neurogenesis : Conserved programs in neocortex, cerebellum, and adult hippocampus
TL;DR: It is found that the same transcription factors are expressed, in the same order, during glutamatergic neurogenesis in the adult dentate gyrus, and in the developing cerebellum, suggesting it is part of a conserved genetic program that specifies general properties of glutamatersgic neurons in these regions.
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Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex.
Tom Kowalczyk,Adria Pontious,Chris Englund,Ray A. M. Daza,Francesco Bedogni,Rebecca D. Hodge,Alessio Attardo,Chris Bell,Wieland B. Huttner,Robert F. Hevner +9 more
TL;DR: Analysis of neurogenic divisions indicated that INPs may produce the majority of projection neurons for preplate, deep, and superficial layers, and proliferative INP divisions increased from early to middle corticogenesis, concomitant with SVZ growth.
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Role of intermediate progenitor cells in cerebral cortex development.
TL;DR: It is proposed that regulation of IPC genesis and amplification across developmental stages and regional subdivisions modulates laminar neurogenesis and contributes to the cytoarchitectonic differentiation of cortical areas.
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Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip.
Andrew J. Fink,Chris Englund,Ray A. M. Daza,Diane Pham,Charmaine Lau,Mary Nivison,Tom Kowalczyk,Robert F. Hevner +7 more
TL;DR: This paper found that deep cerebellar nuclei (DCN) neurons in mice are produced in the rhombic lip and migrate rostrally in a subpial stream to the nuclear transitory zone (NTZ).