Christelle Langley

TL;DR: This preHD cohort is one of the earliest yet studied, and its findings could be used to inform decisions about when to initiate a potential future intervention to delay or prevent further neurodegeneration while function is intact.

TL;DR: Commercially available computerised cognitive games are effective in improving cognitive function in participants without cognitive impairment aged over 60 years, according to a meta-analysis of randomized controlled trials.

TL;DR: In this paper , the authors identified a nonlinear association between sleep, with approximately 7h as the optimal sleep duration, and genetic and cognitive factors, brain structure, and mental health as key measures.

TL;DR: In this article, the authors analyzed game scores and the processing speed obtained over the course of 100 sessions in 12,000 subjects aged 60 to over 80 years, and found that users who trained with the games improved regardless of age in terms of scores and processing speed throughout the 100 sessions, suggesting that old and very old adults can improve their cognitive performance using CMG in real-life use.

TL;DR: It is demonstrated that bumetanide is safe and effective in improving the core symptoms of ASD, and clinical significance remains uncertain, and future multi-center clinical trials are required to replicate these findings and confirm the clinical significance using a variety of outcome measures.