C
Christian Bailly
Researcher at French Institute of Health and Medical Research
Publications - 165
Citations - 6300
Christian Bailly is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: DNA & Topoisomerase. The author has an hindex of 45, co-authored 162 publications receiving 5994 citations. Previous affiliations of Christian Bailly include University of La Rochelle & University of London.
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Topoisomerase I Poisons and Suppressors as Anticancer Drugs
TL;DR: This review is concerned with the different families of topoisomerase I poisons and suppressors, which constitute a novel family of antitumor agents and their origin, chemical nature and mechanism of action.
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Lamellarins, from A to Z: a family of anticancer marine pyrrole alkaloids.
TL;DR: Inhibition of HIV-1 integrase by lamellarin alpha 20-sulfate and human topoisomerase I by lameLLarin D and Molluscum contagiosum virus topoisomersase by lamelliarin H, provide an experimental basis indicating that DNA manipulating enzymes are important targets for the lamellarins.
Journal Article
Lamellarin D: a novel potent inhibitor of topoisomerase I.
Michael Facompré,Christelle Tardy,Christine Bal-Mahieu,Pierre Colson,Carlos A. Perez,Ignacio Manzanares,Carmen Cuevas,Christian Bailly +7 more
TL;DR: The identification and characterization of a novel potent inhibitor of DNA topoisomerase I: lamellarin D (LAM-D), initially isolated from a marine mollusk, Lamellaria sp.
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Anti-proliferative and apoptotic effects of anandamide in human prostatic cancer cell lines: implication of epidermal growth factor receptor down-regulation and ceramide production.
TL;DR: Anandamide (ANA) is an endogenous lipid which acts as a cannabinoid receptor ligand and with potent anticarcinogenic activity in several cancer cell types.
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Mitochondrial proliferation during apoptosis induced by anticancer agents: effects of doxorubicin and mitoxantrone on cancer and cardiac cells.
Jerome Kluza,Philippe Marchetti,Miguel-Angel Gallego,Steve Lancel,Charles Fournier,Anne Loyens,Jean-Claude Beauvillain,Christian Bailly +7 more
TL;DR: The proliferation of mitochondria could explain the higher toxicity of doxorubicin to cancer cells compared to cardiac cells and this suggests novel therapeutic opportunities to better control the cardiotoxicity of anthracyclines.