C
Christian Ehnholm
Researcher at National Institutes of Health
Publications - 82
Citations - 7037
Christian Ehnholm is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Cholesterol & Lipoprotein. The author has an hindex of 38, co-authored 82 publications receiving 6696 citations. Previous affiliations of Christian Ehnholm include Helsinki University Central Hospital & National Institute for Health and Welfare.
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Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial.
Anthony C Keech,R. J. Simes,Philip J. Barter,James D. Best,Russell S. Scott,Marja-Riitta Taskinen,Peta M. Forder,Avinesh Pillai,Tamara M. Davis,Paul Glasziou,Paul L. Drury,Y A Kesäniemi,David R. Sullivan,D Hunt,Peter G. Colman,Michael C d'Emden,Malcolm J. Whiting,Christian Ehnholm,Markku Laakso +18 more
TL;DR: Fenofibrate did not significantly reduce the risk of the primary outcome of coronary events, but it did reduce total cardiovascular events, mainly due to fewer non-fatal myocardial infarctions and revascularisations.
Journal ArticleDOI
The Gln-Arg191 Polymorphism of the Human Paraoxonase Gene (HUMPONA) Is Not Associated with the Risk of Coronary Artery Disease in Finns
Marjatta Antikainen,S. Murtomäki,Mikko Syvänne,Raija Pahlman,Esa Tahvanainen,Matti Jauhiainen,M H Frick,Christian Ehnholm +7 more
TL;DR: The frequency of paraoxonase A and G alleles in 380 well-characterized CAD patients and in 169 controls and the genotype distributions were similar to those reported earlier in other caucasoid populations are found.
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Apolipoprotein E Polymorphism Predicts Death From Coronary Heart Disease in a Longitudinal Study of Elderly Finnish Men
Jari H. Stengård,Kim E. Zerba,Juha Pekkanen,Christian Ehnholm,Aulikki Nissinen,Charles F. Sing +5 more
TL;DR: Allelic variation in the apoE gene is a statistically significant predictor of CHD death in these samples of elderly Finnish men.
Journal ArticleDOI
Type 2 diabetes: Evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs
Soumitra Ghosh,Richard M. Watanabe,Elizabeth R. Hauser,Timo T. Valle,Victoria L. Magnuson,Michael R. Erdos,Carl D. Langefeld,James E. Balow,Delphine S. Ally,Kimmo Kohtamäki,Peter S. Chines,Gunther Birznieks,Hong-Shi Kaleta,Anjene Musick,Catherine Te,Joyce Tannenbaum,William Eldridge,Shane A. Shapiro,Colin Martin,Alyson Witt,Alistair So,Jennie Chang,Ben Shurtleff,Rachel Porter,Kristina Kudelko,Arun M. Unni,Leonid Segal,Ravi Sharaf,Jillian Blaschak-Harvan,Johan G. Eriksson,Tuula Tenkula,Gabriele Vidgren,Christian Ehnholm,Eva Tuomilehto-Wolf,William Hagopian,Thomas A. Buchanan,Jaakko Tuomilehto,Richard N. Bergman,Francis S. Collins,Michael Boehnke +39 more
TL;DR: Evidence from this and other studies suggests at least two diabetes-susceptibility genes on chromosome 20, which has been screened for maturity-onset diabetes of the young 1, hepatic nuclear factor 4-a (HNF-4alpha) in 64 affected sibships with evidence for high chromosomal sharing at its location on chromosomes 20q.
ApoE polymorphism and predisposition to coronary heart disease in youths of different european populations : the EARS study
Laurence Tiret,P. De Knijff,Hans-Jürgen Menzel,Christian Ehnholm,Viviane Nicaud,L.M. Havekes +5 more
TL;DR: A significant association of the apoE polymorphism with a paternal history of myocardial infarction with age- and sex-matched control subjects was found and was consistent across regions, except in the south.