C
Christian Godon
Researcher at Université Paris-Saclay
Publications - 3
Citations - 1322
Christian Godon is an academic researcher from Université Paris-Saclay. The author has contributed to research in topics: Saccharomyces cerevisiae & Thioredoxin. The author has an hindex of 3, co-authored 3 publications receiving 1299 citations.
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Journal ArticleDOI
The H2O2 Stimulon in Saccharomyces cerevisiae
Christian Godon,Gilles Lagniel,Jaekwon Lee,Jean Marie Buhler,Sylvie Kieffer,Michel Perrot,Hélian Boucherie,Michel B. Toledano,Jean Labarre +8 more
TL;DR: This study represents the first genome-wide characterization of a H2O2-inducible stimulon in a eukaryote and results in the resetting of carbohydrate metabolism minutes after the exposure to H2 O2.
Journal ArticleDOI
Yap1 and Skn7 Control Two Specialized Oxidative Stress Response Regulons in Yeast
Jaekwon Lee,Christian Godon,Gilles Lagniel,Daniel Spector,Daniel Spector,Jérôme Garin,Jean Labarre,Michel B. Toledano,Michel B. Toledano +8 more
TL;DR: Remarkably, these two gene subsets separate antioxidant scavenging enzymes from the metabolic pathways regenerating the main cellular reducing power, glutathione and NADPH, and may explain, at least in part, the dissociated function of Yap1 and Skn7 in H2O2 and cadmium resistance.
Journal ArticleDOI
A New Antioxidant with Alkyl Hydroperoxide Defense Properties in Yeast
Jaekwon Lee,Daniel Spector,Daniel Spector,Christian Godon,Jean Labarre,Michel B. Toledano,Michel B. Toledano +6 more
TL;DR: The characterization of AHP1 is reported, which encodes a 19-kDa protein similar to the AhpC/TSA protein family within a small region encompassing Cys-62 of Ahp1p and the highly conserved N-terminal catalytic Ahp C/Tsa cysteine, suggesting a peroxisomal localization.