C
Christian Hofstetter
Researcher at Goethe University Frankfurt
Publications - 28
Citations - 1007
Christian Hofstetter is an academic researcher from Goethe University Frankfurt. The author has contributed to research in topics: Isoflurane & Inhalation. The author has an hindex of 20, co-authored 28 publications receiving 946 citations. Previous affiliations of Christian Hofstetter include University of Mannheim & University of Granada.
Papers
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Journal ArticleDOI
Comparison of direct and video-assisted views of the larynx during routine intubation
Marshal B. Kaplan,Carin A. Hagberg,Denham S. Ward,Ansgar M. Brambrink,Ashwani K. Chhibber,Thomas Heidegger,Leonardo J. Lozada,Andranik Ovassapian,David Roy Parsons,James Ramsay,Wolfram Wilhelm,Bernhard Zwissler,Haus J. Gerig,Christian Hofstetter,Suzanne Karan,Nevin Kreisler,Robert M. Pousman,Andreas Thierbach,M. Wrobel,George Berci +19 more
TL;DR: Video-assisted laryngoscopy provides an improved view of the larynx, as compared with direct visualization, and may be useful for cases of difficult intubation and reintubation as well as for teaching laryNGoscopy and intubations.
Journal ArticleDOI
Protective properties of inhaled IL-22 in a model of ventilator-induced lung injury.
Sandra Hoegl,Malte Bachmann,Patrick Scheiermann,Itamar Goren,Christian Hofstetter,Josef Pfeilschifter,Bernhard Zwissler,Heiko Mühl +7 more
TL;DR: The hypothesis that IL-22, likely via activation of STAT3 and downstream genes (e.g., SOCS3), is able to protect against cell stretch and pulmonary baro-/biotrauma by enhancing epithelial cell resistibility is supported.
Journal ArticleDOI
Anti-inflammatory effects of sevoflurane and mild hypothermia in endotoxemic rats.
Christian Hofstetter,Kim A. Boost,M. Flondor,E. Basagan-Mogol,C. Betz,M. Homann,Heiko Mühl,Josef Pfeilschifter,Bernhard Zwissler +8 more
TL;DR: Volatile anesthetics and hypothermia attenuate the inflammatory response and compare the anti‐inflammatory effects of sevoflurane and mild hypotheria during experimental endotoxemia in the rat.
Journal ArticleDOI
Targeting caspase-1 by inhalation-therapy: effects of Ac-YVAD-CHO on IL-1β, IL-18 and downstream proinflammatory parameters as detected in rat endotoxaemia
Kim A. Boost,S. Hoegl,Christian Hofstetter,M. Flondor,Klaus Stegewerth,Ilka Platacis,Josef Pfeilschifter,Heiko Mühl,Bernhard Zwissler +8 more
TL;DR: It is demonstrated that administration of the caspase-1 inhibitor Ac-YVAD-CHO by inhalation is able to reduce the pulmonary and systemic release of proinflammatory mediators in rat endotoxaemia and underscores that inhalation may constitute an effective route of anti-inflammatory drug administration, beneficial in the clinical setting of ARDS.
Journal ArticleDOI
Isoflurane inhalation after induction of endotoxemia in rats attenuates the systemic cytokine response.
TL;DR: Inhalation of 1 MAC isoflurane after induction of endotoxemia in rats attenuates the systemic release of proinflammatory cytokines and concurrently enhances the production of nitrite in cultured alveolar macrophages.