C
Christian von Loeffelholz
Researcher at University of Jena
Publications - 34
Citations - 991
Christian von Loeffelholz is an academic researcher from University of Jena. The author has contributed to research in topics: Insulin resistance & Fatty liver. The author has an hindex of 16, co-authored 29 publications receiving 804 citations. Previous affiliations of Christian von Loeffelholz include Schiller International University & Charité.
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Journal ArticleDOI
Effects of supplemented isoenergetic diets differing in cereal fiber and protein content on insulin sensitivity in overweight humans
Martin O. Weickert,Michael Roden,Frank Isken,D Hoffmann,Peter Nowotny,Martin A. Osterhoff,Michael Blaut,Carl Alpert,Özlem Gögebakan,C Bumke-Vogt,Friederike Mueller,Jürgen Machann,Thomas M. Barber,Klaus J. Petzke,Johannes Hierholzer,Silke Hornemann,Michael Kruse,Anne-Kathrin Illner,Angela Kohl,Christian von Loeffelholz,Ayman M. Arafat,Matthias Möhlig,Andreas Pfeiffer +22 more
TL;DR: Greater changes in insulin sensitivity after intake of an isoenergetic HCF than after Intake of an HP diet might help to explain the diverse effects of these diets on diabetes risk.
Journal ArticleDOI
WISP1 Is a Novel Adipokine Linked to Inflammation in Obesity
V Murahovschi,Olga Pivovarova,Iryna Ilkavets,Renata M. Dmitrieva,S Döcke,Farnaz Keyhani-Nejad,Özlem Gögebakan,Martin A. Osterhoff,Margrit Kemper,Silke Hornemann,Mariya Markova,Nora Klöting,Martin Stockmann,Martin O. Weickert,V Lamounier-Zepter,Peter Neuhaus,Alexandra Konradi,Steven Dooley,Christian von Loeffelholz,Matthias Blüher,Andreas Pfeiffer,Natalia Rudovich +21 more
TL;DR: The data suggest that WISP1 may play a role in linking obesity to inflammation and insulin resistance and could be a novel therapeutic target for obesity.
Journal ArticleDOI
Circulating vaspin is unrelated to insulin sensitivity in a cohort of nondiabetic humans.
Christian von Loeffelholz,Matthias Möhlig,Ayman M. Arafat,Frank Isken,Joachim Spranger,Knut Mai,Harpal S. Randeva,Andreas Pfeiffer,Martin O. Weickert +8 more
TL;DR: The results support the existence of a sexual dimorphism regarding circulating vaspin regarding insulin sensitivity in nondiabetic humans, and the lack of an association of serum vaspIn with HOMA-IR and M value indicates, however, no major role for vasp in concerning insulin sensitivityIn nondi diabetic humans.
Journal ArticleDOI
Dietary rapeseed/canola-oil supplementation reduces serum lipids and liver enzymes and alters postprandial inflammatory responses in adipose tissue compared to olive-oil supplementation in obese men.
Michael Kruse,Christian von Loeffelholz,D Hoffmann,Antje Pohlmann,AC Seltmann,Martin A. Osterhoff,Silke Hornemann,Olga Pivovarova,Sascha Rohn,Gerhard Jahreis,Andreas Pfeiffer +10 more
TL;DR: It is demonstrated that consuming RA for 4 wk improves serum lipids, liver enzymes, and basal inflammation in s.
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Conjugated linoleic acids: Physiological effects in animal and man with special regard to body composition
TL;DR: Further research is essential to characterize the multifunctionality of CLA in humans, in order to identify the specific physiological mechanism of the biologically active isomers and to determine the optimal level of these isomers for beneficial effects.