T
Thomas M. Barber
Researcher at University of Warwick
Publications - 131
Citations - 4496
Thomas M. Barber is an academic researcher from University of Warwick. The author has contributed to research in topics: Polycystic ovary & Medicine. The author has an hindex of 27, co-authored 111 publications receiving 3250 citations. Previous affiliations of Thomas M. Barber include Imperial College London & Coventry Health Care.
Papers
More filters
Journal ArticleDOI
Obesity and polycystic ovary syndrome
TL;DR: The various mechanisms that might underlie the link between excess adiposity and PCOS are considered – including the effects of differential insulin sensitivity, abnormal steroid hormone metabolism and adipocytokine secretion.
Journal ArticleDOI
Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations
M. Geoffrey Hayes,Margrit Urbanek,David A. Ehrmann,Loren L. Armstrong,Ji Young Lee,Ryan Sisk,Tugce Karaderi,Thomas M. Barber,Mark I. McCarthy,Stephen Franks,Cecilia M. Lindgren,Cecilia M. Lindgren,Corrine K. Welt,Evanthia Diamanti-Kandarakis,Dimitrios Panidis,Mark O. Goodarzi,Ricardo Azziz,Yi Zhang,Roland James,Michael Olivier,Ahmed H. Kissebah,Elisabet Stener-Victorin,Richard S. Legro,Andrea Dunaif,Ruben Alvero,Huiman X. Barnhart,Valerie L. Baker,Kurt T. Barnhart,G. Wright Bates,Robert G. Brzyski,Bruce R. Carr,Sandra Ann Carson,Peter R. Casson,Nicholas A. Cataldo,Gregory M. Christman,Christos Coutifaris,Michael P. Diamond,Esther Eisenberg,Gabriella G. Gosman,Linda C. Giudice,Daniel J. Haisenleder,Hao Huang,Stephen A. Krawetz,Scott Lucidi,Peter G. McGovern,Evan R. Myers,John E. Nestler,Dana A. Ohl,Nanette Santoro,William D. Schlaff,Peter J. Snyder,Michael P. Steinkampf,J. C. Trussell,Rebecca S. Usadi,Qingshang Yan,Heping Zhang +55 more
TL;DR: Common genetic susceptibility loci in European ancestry women for the National Institutes of Health PCOS phenotype are identified, which confers the highest risk for metabolic morbidities, as well as reproductive hormone levels, and implicate neuroendocrine changes in disease pathogenesis.
Journal ArticleDOI
Metabolic characteristics of women with polycystic ovaries and oligo-amenorrhoea but normal androgen levels: implications for the management of polycystic ovary syndrome.
TL;DR: This work characterized the metabolic and endocrine profiles of PCOS women who are oligomenorrhoeic but normoandrogenaemic, and compared these to otherPCOS women and controls.
Journal ArticleDOI
The health benefits of dietary fibre
TL;DR: Given the plethora of scientific evidence that corroborate the multiple and varied health benefits of dietary fibre, and the risks associated with a diet that lacks fibre, the optimization of fibre within the authors' diets represents an important public health strategy to improve both metabolic and overall health.
Journal ArticleDOI
PTEN Mutations as a Cause of Constitutive Insulin Sensitivity and Obesity
Aparna Pal,Thomas M. Barber,Martijn van de Bunt,Simon A. Rudge,Qifeng Zhang,Katherine Lachlan,Nicola S. Cooper,Helen Linden,Jonathan C. Levy,Michael J.O. Wakelam,Lisa Walker,Fredrik Karpe,Anna L. Gloyn +12 more
TL;DR: An apparently divergent effect of PTEN mutations is demonstrated: increased risks of obesity and cancer but a decreased risk of type 2 diabetes owing to enhanced insulin sensitivity.