Christin Reissig

TL;DR: The data reveal a central role of the innate immune system, namely Toll-like receptor 3, to mediate angiogenesis upon release of cytoplasmic RNAs by mechanotransduction of SWT.

TL;DR: Overall, the absence of TLR-3 is associated with lower cumulative kidney damage and maintained renal blood perfusion within the first 24 hours of reperfusion and it is concluded that TLr-3 seems to participate in the pathogenesis of early acute kidney injury.

TL;DR: It is concluded that prednisolone as an additive to the perfusion solution protects from hypoxia triggered danger signals already in the phase of ischemia and thus reduces graft edema in the phases of reperfusion and also leads to macrophage polarization as a beneficial long-term effect.

TL;DR: It is concluded that the combination of objective threshold determination and multiple filtering of the signal gives reliable ABR thresholds comparable to cochlear threshold curves.

TL;DR: VEGF-A directly contributes to the formation of a reperfusion edema, which might be reduced by its blockade, however, the &agr;-VEGF effect on the endothelial integrity might also favor arterial thrombosis formation.