C
Christina M. Laukaitis
Researcher at University of Arizona
Publications - 52
Citations - 1758
Christina M. Laukaitis is an academic researcher from University of Arizona. The author has contributed to research in topics: Gene & Gene family. The author has an hindex of 19, co-authored 48 publications receiving 1615 citations. Previous affiliations of Christina M. Laukaitis include Butler University & Fred Hutchinson Cancer Research Center.
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Journal ArticleDOI
Differential Dynamics of α5 Integrin, Paxillin, and α-Actinin during Formation and Disassembly of Adhesions in Migrating Cells
TL;DR: To investigate the mechanisms by which adhesions form and disperse in migrating cells, α5 integrin, α-actinin, and paxillin were expressed as green fluorescent protein (GFP) fusions that localized with their endogenous counterparts and did not perturb migration when expressed at moderate levels.
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A Phase 3 Trial of Sebelipase Alfa in Lysosomal Acid Lipase Deficiency.
Barbara K. Burton,Manisha Balwani,François Feillet,Ivo Barić,T. Andrew Burrow,Carmen Camarena Grande,Mahmut Çoker,Alejandra Consuelo-Sanchez,Patrick Deegan,Maja Di Rocco,Gregory M. Enns,Richard W. Erbe,Fatih Süheyl Ezgü,Can Ficicioglu,Katryn N. Furuya,John P. Kane,Christina M. Laukaitis,Eugen Mengel,Edward G. Neilan,Scott Nightingale,Heidi Peters,Maurizio Scarpa,K Otfried Schwab,Vratislav Smolka,Vassili Valayannopoulos,Marnie Wood,Zachary Goodman,Yijun Yang,Stephen Eckert,Sandra Rojas-Caro,Anthony G. Quinn +30 more
TL;DR: Sbelipase alfa therapy resulted in a reduction in multiple disease-related hepatic and lipid abnormalities in children and adults with lysosomal acid lipase deficiency and observed improvements in lipid levels and reduction in hepatic fat content.
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Visualizing muscle cell migration in situ.
Brian Knight,Christina M. Laukaitis,Nasreen Akhtar,Neil A. Hotchin,Magnus Edlund,Alan Rick Horwitz,Alan Rick Horwitz +6 more
TL;DR: The observation of cellular migration and the dynamics of molecular organization at high temporal and spatial resolution in situ is feasible, and migration from the somite to the wing bud is discontinuous and not highly stereotyped.
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Salivary androgen-binding protein (abp) mediates sexual isolation in mus musculus.
TL;DR: In this paper, the microevolution of the mouse salivary androgen-binding protein (ABP) Alpha subunit gene (Abpa) has been studied in a laboratory setting and it has been shown that females of the two subspecies are able to discriminate between males of those subspecies on the basis of this protein molecule.
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Reinforcement selection acting on the European house mouse hybrid zone
Barbora Vošlajerová Bímová,Miloš Macholán,Stuart J. E. Baird,Pavel Munclinger,Petra Dufková,Christina M. Laukaitis,Robert C. Karn,Ken Luzynski,Priscilla K. Tucker,Jaroslav Piálek +9 more
TL;DR: In this article, the authors studied two mate recognition signal systems, based on urinary and salivary proteins, across a Central European portion of the mouse hybrid zone, and developed a model for the analysis of the transition of such traits under reinforcement selection.