Christina Tsigalou

TL;DR: A mechanistic basis is provided for a pivotal role of complement and NETs in COVID-19 immunothrombosis and supports strategies against SARS-CoV-2 that exploit complement or NETosis inhibition.

TL;DR: The present preliminary report collected and synthesized early data concerning epidemiological trends and clinical features of the ongoing monkeypox outbreak and compared them with those of previous outbreaks, finding that being fully virally suppressed and undetectable may protect against a more severe infectious course.

TL;DR: Findings indicate Treg involvement in the pathophysiology of MDS; defective suppressor function and BM trafficking of Tregs may be important in the autoimmune process of early MDS, but increased Treg activity could favor leukemic clone progression in late stage disease.

TL;DR: Further large-scale Randomized Controlled Trials (RCTs) in humans are required to evaluate the beneficial properties of probiotics, prebiotic, synbiotics, and postbiotics; their ideal dose; the duration of supplementation; and the durability of their beneficial effects as well as their safety profile in the prevention and management of obesity.

TL;DR: In this article, a review of the antimicrobial activity of plant-derived components, their possible mechanisms of action, as well as their chemical potential, is presented, where the focus is put on the current challenges and future perspectives surrounding medicinal plants antimicrobial efficacy.