E
Eleni Sertaridou
Publications - 5
Citations - 568
Eleni Sertaridou is an academic researcher. The author has contributed to research in topics: Complement system & Neutrophil extracellular traps. The author has an hindex of 3, co-authored 4 publications receiving 246 citations.
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Journal ArticleDOI
Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis.
Panagiotis Skendros,Alexandros Mitsios,Akrivi Chrysanthopoulou,Dimitrios C. Mastellos,Simeon Metallidis,Petros I. Rafailidis,Maria Ntinopoulou,Eleni Sertaridou,Victoria Tsironidou,Christina Tsigalou,Maria G Tektonidou,Theocharis Konstantinidis,Charalampos Papagoras,Ioannis Mitroulis,Georgios Germanidis,John D. Lambris,Konstantinos Ritis +16 more
TL;DR: A mechanistic basis is provided for a pivotal role of complement and NETs in COVID-19 immunothrombosis and supports strategies against SARS-CoV-2 that exploit complement or NETosis inhibition.
Posted ContentDOI
Complement and tissue factor-enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis
Panagiotis Skendros,Alexandros Mitsios,Akrivi Chrysanthopoulou,Dimitrios C. Mastellos,Simeon Metallidis,Petros I. Rafailidis,Maria Ntinopoulou,Eleni Sertaridou,Victoria Tsironidou,Christina Tsigalou,Maria G Tektonidou,Theocharis Konstantinidis,Charalampos Papagoras,Ioannis Mitroulis,Georgios Germanidis,John D. Lambris,Konstantinos Ritis +16 more
TL;DR: A mechanistic basis is provided that reveals the pivotal role of complement and NETs in COVID-19 immmunothrombosis and supports emerging strategies against SARS-CoV-2 infection that exploit complement therapeutics or NETosis inhibition.
Journal ArticleDOI
The Activin/Follistatin-axis is severely deregulated in COVID-19 and independently associated with in-hospital mortality.
Evgenia Synolaki,Vasileios Papadopoulos,Georgios Divolis,Olga Tsahouridou,Efstratios Gavriilidis,Georgia Loli,Ariana Gavriil,Christina Tsigalou,Nikolaos Tziolos,Eleni Sertaridou,Bhanu Kalra,Ajay Kumar,Petros I. Rafailidis,Arja Pasternack,Dimitrios T. Boumpas,Georgios Germanidis,Olli Ritvos,Simeon Metallidis,Panagiotis Skendros,Paschalis Sideras +19 more
TL;DR: This study unravels strong link between Activin/Follistatin-axis and COVID-19 mortality and introduces FACT-CLINYCoD, a novel pathophysiology-based tool that allows dynamic prediction of disease outcome, supporting clinical decision making.
Posted ContentDOI
Activin/Follistatin-axis deregulation is independently associated with COVID-19 in-hospital mortality
Evgenia Synolaki,Vasileios Papadopoulos,Georgios Divolis,Olga Tsachouridou,Efstratios Gavriilidis,Georgia Loli,Arriana Gavriil,Christina Tsigalou,Nikolaos Tziolos,Eleni Sertaridou,Bhanu Kalra,Ajay Kumar,Petros I. Rafailidis,Arja Pasternack,Dimitrios T. Boumpas,Georgios Germanidis,Olli Ritvos,Symeon Metalidis,Panagiotis Skendros,Paschalis Sideras +19 more
TL;DR: This study unravels the link between Activin/Folistatin-axis and COVID-19 mortality and introduces FACT-CLINYCoD, a novel pathophysiology-based tool that copes with the dynamic and heterogeneous nature of COC VID-19, predicts disease outcome and supports clinical decision making.
Journal ArticleDOI
Poor timing and failure of source control are risk factors for mortality in critically ill patients with secondary peritonitis
Gennaro De Pascale,Mieke Deschepper,Kostoula Arvaniti,K Blot,Benton Brown,Jan J. De Waele,George Dimopoulos,Christian Eckmann,Guy Francois,Sonia Labeau,Jeffrey Lipman,Fernando Lipovetsky,José Artur Paiva,Jordi Rello,Dirk Vogelaers,Stijn Blot,Amin Lamrous,Cecilia Pereyra,Fernando Lipovestky,Despoina Koulenti,Joao B Rezende-Neto,Tomas Vymazal,Hans Fjeldsøe Nielsen,Philippe Montravers,Matthias Kott,Arvaniti Kostoula,Yash Javeri,Massimo Girardis,Sharon Einav,Dylan W. de Lange,Luis Daniel Umezawa Makikado,Adam Mikstacki,Dana Tomescu,A.I. Gritsan,Bojan Jovanovic,Kumaresh Venkatesan,Tomislav Mirkovic,Emilio Maseda,Yalım Dikmen,M. Emmerich,María José Canale,L. S. Dietz,Santiago Ilutovich,John Thomas Sanchez Miñope,Ramona Silva,M Montenegro,P. Martin,Pablo Saúl,Viviana Chediack,Giselle Sutton,Rocío N. Couce,Carina Balasini,Susana Gonzalez,F. Lascar,Emiliano Descotte,Natalia Soledad Gumiela,Carina Alejandra Pino,Cristián Emanuel Cesio,Emanuel Valgolio,Eleonora Roxana Cunto,Cecilia Verónica Domínguez,Nydia Funes Nelson,Esteban Martin Abegao,N. C. Pozo,Luciana Bianchi,E. Correger,M. Pastorino,Erica A. Miyazaki,Nicolas Grubissich,Mariel Garcia,Natalia Bonetto,N. Quevedo,Cristina Delia Gomez,Felipe Queti,Luis Gonzalez Estevarena,Ruben O. Fernandez,Ignacio Santolaya,Sergio Hugo Grangeat,Juan Doglia,Graciela Zakalik,C. Pellegrini,Mariano Lloria,M. E. Chacon,M. Fumale,Mariela Leguizamon,Irene Hidalgo,Roberto Julian Tiranti,P. Castillo Capponi,Agustin Tita,Luis Pablo Cardonnet,Lisandro R. Bettini,Agñel Ramos,L. Lovesio,Edith Miranda,Angelica Beatriz Farfan,Carina Tolosa,Lise Segura,Adelina Bellocchio,B. Alvarez,Adriana Manzur,R. Lujan,Natalia Fernandez,Nahuel Scarone,Alan Zazu,Carina Groh,Jason M. Fletcher,Julie Smith,Raman Azad,Nitin Chavan,Mark Kol,Lewis Campbell,Therese Starr,Brigit Roberts,Bradley Wibrow,T. Warhurst,Meher P Chinthamuneedi,Bernal Buitrago Ferney,M. Simon,Daniel De Backer,Xavier Wittebole,David De Bels,Vincent Collin,Karolien Dams,Philippe G. Jorens,Jasperina Dubois,Jan Gunst,Lionel L Haentjens,Nicolas De Schryver,Thierry Dugernier,Sandro Rizoli,Paulino Sánchez-Santillán,Yi Han,Ewelina Biskup,Chang Qu,Xinyu Li,Tao Yu,Lu Weihua,Daniel Molano-Franco,Jose Nicolas Rojas,J.M. Pardo Oviedo,Darío Pinilla,Yenny Cardenas,Edgar Celis,Mario Ramón García Arias,Anita Vukovic,Maja Vudrag,Matija Belavić,Josip Zunic,Janja Kuharić,Irena Božanić Krička,Ina Filipović-Grčić,Boris Tomasevic,Melanija Obraz,Bruna Bodulica,M. Dohnal,Jan Maláska,Milan Kratochvil,I Satinský,Peter Schwarz,Zdeněk Kos,Ladislav Blahut,Jan Máca,M. Protus,Eva Kieslichova,Louise Gramstrup Nielsen,Birgitte Marianne Krogh,Francisco Rivadeneira,Freddy Morales,J Bonastre Mora,Alexandra Orozco,Diego Rolando MorochoTutillo,Nelson Vargas,E. S. Yepez,B. Villamagua,Adel Mohamed Yasin Alsisi,Abdelraouf Fahmy,Herve Dupont,Sigismond Lasocki,Catherine Paugam-Burtz,Arnaud Foucrier,Alexandru Nica,Geneviève Barjon,Jihad Mallat,Guillaume Marcotte,Marc Leone,Gary Duclos,P. Burtin,Enora Atchade,Yazine Mahjoub,Benoit Misset,Jean-François Timsit,Claire Dupuis,Benoit Veber,M. Debarre,Olivier Collange,Julien Pottecher,Stéphane Hecketsweiler,Mélanie Fromentin,Antoine Tesniere,Christian Koch,Michael Sander,Gunnar Elke,Hermann Wrigge,Philippe Simon,A Chalkiadaki,C. Tzanidakis,Ioannis Pneumatikos,Eleni Sertaridou,Z. Mastora,Ioannis Panagopoulos,M. Papanikolaou,Theonymfi Papavasilopoulou,John D. Floros,Chryssa Diakaki,Michail Rallis,Alexandra Paridou,A. Kalogeromitros,V. Romanou,Charikleia Nikolaou,Katerina Kounougeri,E. Tsigou,Vasiliki Psallida,Niki Karampela,Konstantinos Mandragos,E. Kontoudaki,Alexandra Pentheroudaki,Christos Farazi-Chongouki,Agathi Karakosta,I Chouris,V. Radu,Polychronis Malliotakis,Sofia Kokkini,Eliana Charalambous,Aikaterini Kyritsi,Vasilios Koulouras,Georgios Papathanakos,Eva Nagky,C Lampiri,Fotios Tsimpoukas,I. Sarakatsanos,Panagiotis Georgakopoulos,I. Ravani,Athanasios A. Prekates,Konstantinos Sakellaridis,Christos Christopoulos,E. Vrettou,Konstantinos Stokkos,Anastasia Pentari,K. Marmanidou,C. Kydona,Georgios Tsoumaropoulos,M. Bitzani,Paschalina Kontou,A Voudouris,E. Flioni,E Antypa,E Chasou,Souzana Anisoglou,Eirini Papageorgiou,Theoniki Paraforou,Agoritsa Tsioka,A Karathanou,A. Vakalos,Bhagyesh Shah,Chirag V Thakkar,Nikhilesh Jain,Mohan Gurjar,Arvind K Baronia,Prachee Sathe,Shilpa Kulkarni,Cherish Paul,John Paul,Mansoor Masjedi,Reza Nikandish,Farid Zand,Golnar Sabetian,Ata Mahmoodpoor,Seyed Mohammadreza Hashemian,Miklosh Bala,Romeo Flocco,S. Torrente,Vincenzo Pota,Savino Spadaro,Carlo Alberto Volta,Giulia Serafini,Sabrina Boraso,Ivo Tiberio,Andrea Cortegiani,Giovanni Misseri,Mario Barbagallo,Davide Nicolotti,Francesco Forfori,Francesco Corradi,Massimo Antonelli,Lorella Pelagalli,Luca Brazzi,Ferdinando Vittone,Alessandro Russo,D Simion,Antonella Cotoia,Gilda Cinnella Patrick Toppin,Roxanne Johnson-Jackson,Yoshihiro Hayashi,Ryohei Yamamoto,Hideto Yasuda,Y Kishihara,Junji Shiotsuka,Luis Alejandro Sánchez-Hurtado,Brigitte Tejeda-Huezo,L. Gorordo,Silvio A. Ñamendys-Silva,Francisco J. García-Guillén,Manuel Palacio Martinez,Erick Romero-Meja,Ever Colorado-Dominguez,Huub L. A. van den Oever,Karel-Martijn Kalff,Wytze J. Vermeijden,Alexander D. Cornet,O. Beck,Nedim Cimic,Tom Dormans,Laura Bormans,Jan Bakker,Ditty van Duijn,G. I. C. G. M. Bosman,P Vos,Jozef Kesecioglu,Lenneke E M Haas,Akram Henein,Ariel Miranda,Gonzalo Malca,Abel Salvador Arroyo-Sánchez,Agnieszka Misiewska-Kaczur,Frisch Akinyi,Mirosław Czuczwar,Karolina Luczak,Wiktor Sułkowski,Barbara Tamowicz,B. Świt,Bronisław Baranowski,Piotr Smuszkiewicz,I. Trojanowska,Stanisław Rzymski,Mariusz Sawinski,Marta Trosiak,Małgorzata Mikaszewska-Sokolewicz,Ricardo Alves,Dina Leal,A. Krystopchuk,P. Mendonca,Rui Pereira,M. R. D. de Carvalho,Carlos Candeias,E. Molinos,Amélia Ferreira,Guiomar Castro,José M. C. Pereira,Lurdes Santos,Alcina Ferreira,Dulce Pascoalinho,R. Ribeiro,Guilherme Domingos,Pedro R. S. Gomes,David Nora,R. Costa,A. Santos,Ahmed Subhy Humadi Alsheikhly,Mihai Popescu,Ioana T. Grigoras,Emilia Patraşcanu,I.B. Zabolotskikh,T. Musaeva,D.V. Gaigolnik,V.V. Kulabukhov,Vladislav Belskiy,Nadezhda Zubareva,M. Tribulev,Ahmed Abdelsalam,Ayman Aldarsani,Muhammad Al-Khalid,Ghaleb A. Almekhlafi,Yasser Mandourah,Krstina Doklestic,Jelena Velickovic,Dejan Velickovic,Radmilo Jankovic,Svetlana Skoric-Jokic,Dragana Radovanovic,Guy A. Richards,A F Alli,del Carmen Cordoba Nielfa,Rafael Sánchez Iniesta,Adela Martinez,Carlos Garcia Bernedo,Santiago Alberto Picos Gil,Xavier Nuvials,J. Garcia,J.M. Pena,Roberto Jiménez,L. Herrera,Laura Barrachina,Ignacio Catalan Monzon,Francisco J Redondo,R. Villazala,Diego Fernando Matallana Zapata,Isabel Maria Villa Lopez,Gabriel Moreno-González,Juan Carlos Lopez-Delgado,Jorge Solera Marín,Purificación Sánchez-Zamora,M. Vallverdú Vidal,Jesus Gonzalez,I. Salinas,Cecilia Hermosa,Fernando Martínez-Sagasti,S. Domingo-Marín,Johanna Abril Victorino,Raquel García-Álvarez,Pablo Calleja,María Victoria de la Torre-Prados,P. V. Vidal-Cortés,L. Del Río-Carbajo,J J Izura,Victoria Mínguez,J. Trenado Álvarez,Anna Parera Prous,Daniela Paz,Ferran Roche-Campo,Gerardo Aguilar,Javier Belda,Jesús Rico-Feijoo,C. Aldecoa,Begoña Zalba-Etayo,Alexander Dullenkopf,Konlawij Trongtrakul,Anusang Chtsomkasem,Türkay Akbaş,Mustafa Necmettin Ünal,Ayca Gumus,Atilla Ramazanoglu,Dilek Memiş,Inal Mehmet,S.S. Urkmez,A. Ozgultekin,Oktay Demirkiran,Nesrin Ahu Aslan,Deniz Kizilaslan,Ferda Kahveci,Nurdan Ünlü,Zeynep Kzlck Ozkan,Callum T Kaye,Jan Jansen,Orla O'Neill,Christopher Nutt,Rajeev Jha,Nicolas Hooker,I. Grecu,Christina Petridou,Murali Shyamsundar,Lia McNamee,John Trinder,Samantha J. Hagan,Catriona Kelly,Jonathon Silversides,Casiano Barrera Groba,Owen Boyd,Kaushik Bhowmick,Sally Humphreys,C. Gail Summers,Petra Polgarova,Michael Margarson,J. Dickens,Suzanne Pearson,Elaine Chinery,Noel Hemmings,S. O’Kane,P. Austin,Stephen Cole,Catherine Plowright,R. Box,C.T. Wright,Lorna Young,Ben Creagh-Brown,Laura Montague,Robert S. Parker,Ben Morton,Marlies Ostermann,Julia Bilinska,Bernd Oliver Rose,R. Reece-Anthony,Christine Ryan,Mark Hamilton,Philip Hopkins,Julia Wendon,G. Brescia,Nazia Ijaz,J Wood,Michelle George,Piroska Toth-Tarsoly,Bryan Yates,N Armstrong,C. Scott,Christina M. Boyd,Tamas Szakmany,D. Rees,Paul Pulak,Mandy Coggon,Bhaskar Saha,Linda Kent,Bethan K. Gibson,Julie Camsooksai,Henrik Reschreiter,Patrick Morgan,S. Jeson Sangaralingham,A Lowe,P Vondras,Sunil Jamadarkhana,C. Cruz,Rakesh Bhandary,Peter Hersey,Julie Furneval,Richard Innes,P G Doble,Benjamin Attwood,Penny Parsons,Valerie J. Page,Xiaopeng Zhao,Julian Dalton,Mohammed A Hegazy,Y Awad,Douglas F. Naylor,Amanda Naylor,Sarah Lee,Sidney B. Brevard,Noelle L. Davis +535 more
TL;DR: In this paper , the authors describe data on epidemiology, microbiology, clinical characteristics and outcome of adult patients admitted in the ICU with secondary peritonitis, with special emphasis on antimicrobial therapy and source control.