C
Christina Y. Kim
Researcher at Tufts University
Publications - 3
Citations - 437
Christina Y. Kim is an academic researcher from Tufts University. The author has contributed to research in topics: Micelle & Gene silencing. The author has an hindex of 2, co-authored 2 publications receiving 418 citations.
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The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis
Jin Xu,Nan Zhong,Haoyong Wang,Joshua E. Elias,Christina Y. Kim,Irina Woldman,Christian Pifl,Steven P. Gygi,Changiz Geula,Bruce A. Yankner +9 more
TL;DR: DJ-1 is a neuroProtective transcriptional co-activator that may act in concert with p54nrb and PSF to regulate the expression of a neuroprotective genetic program.
Journal ArticleDOI
DJ-1 transcriptionally up-regulates the human tyrosine hydroxylase by inhibiting the sumoylation of pyrimidine tract-binding protein-associated splicing factor.
Nan Zhong,Christina Y. Kim,Patrizia Rizzu,Changiz Geula,Douglas R. Porter,Emmanuel N. Pothos,Ferdinando Squitieri,Peter Heutink,Jin Xu +8 more
TL;DR: DJ-1 is suggested as a regulator of protein sumoylation and directly link the loss of DJ-1 expression and transcriptional dysfunction to impaired dopamine synthesis.
Journal ArticleDOI
Recombinant Protein Micelles to Block Transduction by SARS-CoV-2 Pseudovirus
TL;DR: A recombinant amphiphilic protein, oleosin, is engineered to spontaneously self-assemble into multivalent micellar nanostructures which can block the Spike S1 protein of SARS-CoV-2 pseudoviruses (PVs).