C
Christine Allen
Researcher at University of Toronto
Publications - 196
Citations - 12374
Christine Allen is an academic researcher from University of Toronto. The author has contributed to research in topics: Drug delivery & Micelle. The author has an hindex of 53, co-authored 187 publications receiving 10808 citations. Previous affiliations of Christine Allen include Ontario Institute for Cancer Research & University Health Network.
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Journal ArticleDOI
Nano-engineering block copolymer aggregates for drug delivery
TL;DR: The key performance related properties the authors discuss are loading capacity, release kinetics, circulation time, biodistribution, size, size distribution and stability, to allow the reader to tailor-make block copolymer micelles for a particular application.
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Gold nanoparticles for applications in cancer radiotherapy: Mechanisms and recent advancements.
TL;DR: An overview of the current state of AuNP‐based radiosensitization in the context of the physical, chemical and biological modes of radiosensItization is presented, with design considerations to guide the development of next generation AuNPs for clinical applications.
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Gold Nanoparticles as Radiation Sensitizers in Cancer Therapy
Devika B. Chithrani,Salomeh Jelveh,Farid Jalali,Monique van Prooijen,Christine Allen,Robert G. Bristow,Robert G. Bristow,Richard P. Hill,Richard P. Hill,David A. Jaffray,David A. Jaffray +10 more
TL;DR: The results of in vitro studies that focus on the radiosensitization properties of nanoparticles in the size range from 14–74 nm will enable the optimization of gold nanoparticle-based sensitizers for use in therapy.
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Controlling the physical behavior and biological performance of liposome formulations through use of surface grafted poly(ethylene glycol).
Christine Allen,N. Dos Santos,N. Dos Santos,Ryan C. Gallagher,Gigi N.C. Chiu,Gigi N.C. Chiu,Y. Shu,Wai Ming Li,Wai Ming Li,Sharon Johnstone,Andrew S. Janoff,Lawrence D. Mayer,Lawrence D. Mayer,Murray S. Webb,Marcel B. Bally,Marcel B. Bally +15 more
TL;DR: All aspects of PEG are examined in order to gain a better understanding of how the polymer fulfills its biological role and the physical and chemical properties of the polymer are explored and compared to properties of other hydrophilic polymers.
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Polymer–drug compatibility: A guide to the development of delivery systems for the anticancer agent, ellipticine
TL;DR: A good correlation was obtained between drug formulation characteristics and findings from polymer-drug compatibility studies, as a means to guide formulation development.