C
Christine Grossen
Researcher at University of Zurich
Publications - 32
Citations - 1115
Christine Grossen is an academic researcher from University of Zurich. The author has contributed to research in topics: Population & Capra ibex. The author has an hindex of 16, co-authored 29 publications receiving 841 citations. Previous affiliations of Christine Grossen include University of British Columbia & University of Lausanne.
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Journal ArticleDOI
Ever-Young sex chromosomes in European tree frogs
Matthias Stöck,Agnès Horn,Christine Grossen,Dorothea Lindtke,Dorothea Lindtke,Roberto Sermier,Caroline Betto-Colliard,Christophe Dufresnes,Emmanuel Bonjour,Zoé Dumas,Zoé Dumas,Emilien Luquet,Tiziano Maddalena,Helena Clavero Sousa,Iñigo Martínez-Solano,Nicolas Perrin +15 more
TL;DR: It is concluded that sex-chromosome homomorphy in these tree frogs does not result from a recent turnover but is maintained over evolutionary timescales by occasional X-Y recombination, a result at odds with the view that sex chromosomes necessarily decay until they are replaced.
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Purging of highly deleterious mutations through severe bottlenecks in Alpine ibex
TL;DR: It is shown that historic bottlenecks rather than the current conservation status predict levels of genome-wide variation, and it is highlighted that even populations of ~1000 individuals can accumulate mildly deleterious mutations.
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Sex‐chromosome turnovers induced by deleterious mutation load
Olivier Blaser,Christine Grossen,Christine Grossen,Samuel Neuenschwander,Samuel Neuenschwander,Nicolas Perrin +5 more
TL;DR: Individual‐based simulations of a Muller's ratchet process are used to test how the relevant parameters (effective population size, strength and dominance of deleterious mutations, size of nonrecombining segment, and strength of sexually antagonistic selection) are expected to affect the rate of turnovers.
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Temperature‐dependent turnovers in sex‐determination mechanisms: a quantitative model
TL;DR: It is proposed to define sex‐determination systems at the population‐ (rather than individual) level, via the proportion of variance in phenotypic sex stemming from genetic versus environmental factors, and this concept is formalized in a quantitative‐genetics framework.
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Introgression from domestic goat generated variation at the major histocompatibility complex of Alpine ibex.
TL;DR: Evidence for introgression at the major histocompatibility complex in Alpine ibex is provided and contradicts the long-standing view that genetic variability at the MHC is solely a consequence of ancient trans-species polymorphism.