C
Christine Sempoux
Researcher at University of Lausanne
Publications - 357
Citations - 12375
Christine Sempoux is an academic researcher from University of Lausanne. The author has contributed to research in topics: Medicine & Liver transplantation. The author has an hindex of 55, co-authored 326 publications receiving 10647 citations. Previous affiliations of Christine Sempoux include Casa Sollievo della Sofferenza & Université catholique de Louvain.
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Journal ArticleDOI
Pancreatic beta-cell mass in European subjects with type 2 diabetes.
TL;DR: The average β‐cell mass is about 39% lower in T2D subjects compared with matched controls, and its decrease with duration of the disease could be a consequence of diabetes that, with further impairment of insulin secretion, contributes to the progressive deterioration of glucose homeostasis.
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Magnetic Resonance Elastography for the Noninvasive Staging of Liver Fibrosis
Laurent Huwart,Christine Sempoux,Eric Vicaut,Najat Salameh,Laurence Annet,Etienne Danse,François M. Peeters,Leon C. ter Beek,Jacques Rahier,Ralph Sinkus,Yves Horsmans,Bernard E. Van Beers +11 more
TL;DR: Magnetic resonance elastography has a higher technical success rate than ultrasoundElastography and a better diagnostic accuracy than ultrasound elastsography and APRI for staging liver fibrosis.
Journal ArticleDOI
Liver fibrosis: noninvasive assessment with MR elastography versus aspartate aminotransferase-to-platelet ratio index.
Laurent Huwart,Christine Sempoux,Najat Salameh,Jacques Jamart,Laurence Annet,Ralph Sinkus,François M. Peeters,Leon C. ter Beek,Yves Horsmans,Bernard E. Van Beers +9 more
TL;DR: Large A(z) values for elasticity show that MR elastography was accurate in liver fibrosis staging and superior to biochemical testing with APRIs.
Journal ArticleDOI
Clinical features of 52 neonates with hyperinsulinism.
P de Lonlay-Debeney,F. Poggi-Travert,Jean-Christophe Fournet,Christine Sempoux,C D Vici,Francis Brunelle,Guy Touati,Jacques Rahier,Claudine Junien,Claire Nihoul-Fékété,J.-J. Robert,Jean-Marie Saudubray +11 more
TL;DR: Among neonates with hyperinsulinism, about half may have focal islet-cell hyperplasia that can be treated with partial pancreatectomy, and these neonates can be identified through pancreatic catheterization and intraoperative histologic studies.
Journal ArticleDOI
Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues
Ivan Théate,Ivan Théate,Nicolas van Baren,Nicolas van Baren,Luc Pilotte,Luc Pilotte,Pierre Moulin,Pierre Larrieu,Pierre Larrieu,Jean-Christophe Renauld,Jean-Christophe Renauld,Caroline Hervé,Caroline Hervé,Ilse Gutierrez-Roelens,Etienne Marbaix,Etienne Marbaix,Christine Sempoux,Benoît Van den Eynde,Benoît Van den Eynde +18 more
TL;DR: Expression of IDO1 may be used to select tumors likely to benefit from targeted therapy with IDo1 inhibitors, and its expression in normal and tumor tissues was confirmed by gene expression data mined from The Cancer Genome Atlas database.