Christoph A. Lill

TL;DR: It is concluded that application of the techniques investigated here can lead to a better prediction of the bone failure load for bone in vivo than is possible from DXA measurements, structural parameters, or a combination thereof.

TL;DR: It is concluded that the noninvasive diagnosis of loss of strength at the distal radius should rely on site‐specific measurements with DXA or pQCT and may be the earliest chance to detect individuals at risk of osteoporotic fracture.

TL;DR: The data suggest that mechanical competence in the elderly is governed by strong regional variation, and that its loss in osteoporosis may not represent a strictly systemic process.

TL;DR: Testing the hypothesis that peripheral quantitative computed tomography at the distal radius and/or quantitative ultrasound at the calcaneus can serve as replacement or improvement of current methodology for predicting bone strength at the hip and other sites suggests that clinical assessment of femoral fracture risk should preferably rely on femoral DXA.

TL;DR: In this article, a 3D micro-finite element (micro-FE) model based on high-resolution images was used to predict the distal radius strength of 54 cadaver arms.