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Christoph Grouls
Researcher at RWTH Aachen University
Publications - 16
Citations - 431
Christoph Grouls is an academic researcher from RWTH Aachen University. The author has contributed to research in topics: Content-based image retrieval & Image retrieval. The author has an hindex of 10, co-authored 16 publications receiving 392 citations.
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Journal ArticleDOI
Chemokine Cxcl9 attenuates liver fibrosis-associated angiogenesis in mice.
H Sahin,Erawan Borkham-Kamphorst,Christoph Kuppe,Mirko Moreno Zaldivar,Christoph Grouls,M Alsamman,A Nellen,P. Schmitz,D Heinrichs,Marie-Luise Berres,Dennis Doleschel,D. Scholten,Ralf Weiskirchen,Marcus J. Moeller,Fabian Kiessling,Christian Trautwein,Hermann E. Wasmuth +16 more
TL;DR: The results identify direct angiostatic and antifibrotic effects of the Cxcr3 ligand Cxcl9 in a model of experimental liver fibrosis and suggest that the amelioration of liver damage by systemic application of CxCl9 might offer a novel therapeutic approach for chronic liver diseases associated with increased neoangiogenesis.
Journal ArticleDOI
Molecular and functional ultrasound imaging in differently aggressive breast cancer xenografts using two novel ultrasound contrast agents (BR55 and BR38)
Jessica Bzyl,Wiltrud Lederle,Anne Rix,Christoph Grouls,Isabelle Tardy,Sibylle Pochon,Monica Siepmann,Tobias Penzkofer,Michel Schneider,Fabian Kiessling,Moritz Palmowski +10 more
TL;DR: BR38 and BR55 are well suited to characterising and distinguishing breast cancers with different angiogenesis and aggressiveness and allow extensive 3-dimensional examinations of larger or several organs.
Journal ArticleDOI
Virtual Elastic Sphere Processing Enables Reproducible Quantification of Vessel Stenosis at CT and MR Angiography
Felix Gremse,Christoph Grouls,Moritz Palmowski,Twan Lammers,Anke de Vries,Holger Grüll,Marco Das,Georg Mühlenbruch,Shamima Akhtar,Andreas Schober,Fabian Kiessling +10 more
TL;DR: The virtual elastic sphere tool is applicable to CT, dual-energy CT, and MR angiography, and it improves reproducibility and efficiency over that achieved with manual stenosis measurements.
Journal ArticleDOI
Liver dysplasia: US molecular imaging with targeted contrast agent enables early assessment.
Christoph Grouls,Maximillian Hatting,Anne Rix,Sibylle Pochon,Wiltrud Lederle,Isabelle Tardy,Christiane K. Kuhl,Christian Trautwein,Fabian Kiessling,Moritz Palmowski +9 more
TL;DR: BR55 enables the distinction of early stages of liver dysplasia from normal liver in transgenic mice and targeted contrast-enhanced US signal indicated a significantly higher site-specific binding of BR55 in dysplastic than healthy livers.
Journal ArticleDOI
Bridging the integration gap between imaging and information systems: a uniform data concept for content-based image retrieval in computer-aided diagnosis.
Petra Welter,Jörg Riesmeier,Benedikt Fischer,Christoph Grouls,Christiane K. Kuhl,Thomas M. Deserno +5 more
TL;DR: It is suggested that CBIR systems applied to CAD should integrate their results in a picture archiving and communication systems environment such as Digital Imaging and Communications in Medicine (DICOM) structured reporting documents.