C
Christopher J. Creevey
Researcher at Queen's University Belfast
Publications - 122
Citations - 9600
Christopher J. Creevey is an academic researcher from Queen's University Belfast. The author has contributed to research in topics: Microbiome & Gene. The author has an hindex of 32, co-authored 102 publications receiving 8320 citations. Previous affiliations of Christopher J. Creevey include French Institute of Health and Medical Research & Teagasc.
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STRING 8—a global view on proteins and their functional interactions in 630 organisms
Lars Juhl Jensen,Michael Kuhn,Manuel Stark,Samuel Chaffron,Christopher J. Creevey,Jean Muller,T. Doerks,Philippe Julien,Alexander Roth,Milan Simonovic,Peer Bork,Christian von Mering +11 more
TL;DR: The most important new developments in STRING 8 over previous releases include a URL-based programming interface, improved interaction prediction via genomic neighborhood in prokaryotes, and the inclusion of protein structures.
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Toward Automatic Reconstruction of a Highly Resolved Tree of Life
Francesca D. Ciccarelli,Tobias Doerks,Christian von Mering,Christopher J. Creevey,Berend Snel,Peer Bork +5 more
TL;DR: An automatable procedure for reconstructing the tree of life with branch lengths comparable across all three domains is developed, revealing interdomain discrepancies in taxonomic classification and suggesting a thermophilic last universal common ancestor.
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Assessment of methods for amino acid matrix selection and their use on empirical data shows that ad hoc assumptions for choice of matrix are not justified
Thomas M. Keane,Christopher J. Creevey,Melissa M. Pentony,Thomas J. Naughton,James O Mclnerney +4 more
TL;DR: It is demonstrated that for two large datasets derived from the proteobacteria and archaea, one of the most favored models in both datasets is a model that was originally derived from retroviral Pol proteins.
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eggNOG v4.0: nested orthology inference across 3686 organisms
Sean Powell,Kristoffer Forslund,Damian Szklarczyk,Kalliopi Trachana,Alexander Roth,Jaime Huerta-Cepas,Toni Gabaldón,Thomas Rattei,Christopher J. Creevey,Michael Kuhn,Lars Juhl Jensen,Christian von Mering,Peer Bork +12 more
TL;DR: The eggNOG database as mentioned in this paper provides a comprehensive characterization and analysis pipeline to derive nonsupervised orthologous groups (NOGs) from complete genomes, and then applies a comprehensive analysis to the resulting gene families.
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Genome-Wide Experimental Determination of Barriers to Horizontal Gene Transfer
Rotem Sorek,Yiwen Zhu,Christopher J. Creevey,M. Pilar Francino,Peer Bork,Edward M. Rubin,Edward M. Rubin +6 more
TL;DR: The data suggest that toxicity to the host inhibited transfer regardless of the species of origin and that increased gene dosage and associated increased expression may be a predominant cause for transfer failure.